Interaktionen kardialer und antiretroviraler Medikation

Egger, Sabin S.; Drewe, Jürgen

doi:10.1007/s00059-005-2723-4

Herz

2005

DOI: 10.1007/s00059-005-2723-4

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Interaktionen kardialer und antiretroviraler Medikation

Sabin S. Egger

Jürgen Drewe

Abstract: New therapeutic options such as the highly active antiretroviral therapy (HAART) have significantly improved morbidity and mortality of HIV-infected patients. Consequently, age-related diseases become more manifest. In addition, HIV infection itself causes certain cardiovascular morbidity. Therefore, treatment of cardiovascular symptoms of HIV-positive patients becomes more and more important. Pharmacotherapy in these patients is complex and requires polypharmacy with drugs carrying a high risk of drug-drug in… Show more

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2009

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Heart Disease in Patients with HIV/AIDS-An Emerging Clinical Problem

Gopal¹,

Bhaskaran²,

Khalife³

et al. 2009

CCR

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HIV/AIDS (Human immunodeficiency virus/ Acquired immuno deficiency syndrome) is a growing global problem, in terms of its incidence and mortality. Patients with HIV/AIDS are living much longer with HAART (Highly active antiretroviral therapy) therapy so much so that HIV/AIDS has now become a part of the chronic disease burden, like hypertension and diabetes. Patients with HIV/AIDS and symptoms suggestive of cardiac disease represent a diagnostic and therapeutic challenge in clinical practice; Cardiologists are more frequently encountering this problem. An algorithmic, anatomic approach to diagnosis, localizing disease to the endocardium, myocardium and pericardium can be useful. An intimate knowledge of opportunistic infections affecting the heart, effects of HAART therapy and therapy for opportunistic infections on the heart is needed to be able to formulate a differential diagnosis. Effects of HAART therapy, especially protease inhibitors on lipid and glucose metabolism, and their influence on progression to premature vascular disease require consideration. Treatment of cardiac disease, in HIV/AIDS patients can vary from non-HIV patients, based on drug interactions, differences in responsiveness, and other factors; and this area requires further research.

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Heart Disease in Patients with HIV/AIDS-An Emerging Clinical Problem

Gopal¹,

Bhaskaran²,

Khalife³

et al. 2009

CCR

View full text Add to dashboard Cite

show abstract

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Interaktionen kardialer und antiretroviraler Medikation

Cited by 1 publication

References 100 publications

Heart Disease in Patients with HIV/AIDS-An Emerging Clinical Problem

Heart Disease in Patients with HIV/AIDS-An Emerging Clinical Problem

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