INTERACTS (INTErventional Radiotherapy ACtive Teaching School) guidelines for quality assurance in choroidal melanoma interventional radiotherapy (brachytherapy) procedures

Abstract

Eye plaque brachytherapy represents a safe and effective therapeutic approach for choroidal melanoma, combining clinical outcomes with an eye and visual preservation.As it represents a complex procedure, a specific quality assurance program is strongly suggested to improve patients and operators safety, and to reduce possible complications linked to surgical procedure and radiation exposure.The aim of this paper is to describe the INTERACTS (Interventional Radiotherapy Active Teaching School) guidelines for quality assurance in choroidal melanoma interventional radiotherapy (brachytherapy) used in our institution.

BIT-ART: Multicentric Comparison of HDR-brachytherapy, Intensity-modulated Radiotherapy and Tomotherapy for Advanced Radiotherapy in Prostate Cancer

“…Our results confirmed the feasibility and safety of HDR boost escalation as shown in literature in other patient settings (43)(44)(45); even if HDR has to be performed in specialized centers collecting high numbers of patients with Expert Interventional Radiation Oncologist (46,47).…”

BIT-ART: Multicentric Comparison of HDR-brachytherapy, Intensity-modulated Radiotherapy and Tomotherapy for Advanced Radiotherapy in Prostate Cancer

“…Our results confirmed the feasibility and safety of HDR boost escalation as shown in literature in other patient settings (43)(44)(45); even if HDR has to be performed in specialized centers collecting high numbers of patients with Expert Interventional Radiation Oncologist (46,47).…”

Analysis of local recurrence causes in uveal melanoma patients treated with 125I brachytherapy – a single institution study

“…Ophthalmologists skilled in plaque placement surgery, the radiation oncologist and medical physicists were involved in the treatment procedure, making up a multidisciplinary ocular tumour team. The course of the treatment and follow-up were very similar to that described by Tagliaferri et al [12].…”

Clinical evidence of abscopal effect in cutaneous squamous cell carcinoma treated with diffusing alpha emitters radiation therapy: a case report

“…These evidences will further support recent findings on radiation used as immunological adjuvant in numerous clinical scenarios, also in advanced stage diseases [41,42]. Finally, DaRT technique is not complex; however, is still relatively new and requires standardization and specific training as other brachytherapy technique [43,44,45,46].…”

BIT-ART: Multicentric Comparison of HDR-brachytherapy, Intensity-modulated Radiotherapy and Tomotherapy for Advanced Radiotherapy in Prostate Cancer

“…Our results confirmed the feasibility and safety of HDR boost escalation as shown in literature in other patient settings (43)(44)(45); even if HDR has to be performed in specialized centers collecting high numbers of patients with Expert Interventional Radiation Oncologist (46,47).…”

Analysis of local recurrence causes in uveal melanoma patients treated with 125I brachytherapy – a single institution study

“…Ophthalmologists skilled in plaque placement surgery, the radiation oncologist and medical physicists were involved in the treatment procedure, making up a multidisciplinary ocular tumour team. The course of the treatment and follow-up were very similar to that described by Tagliaferri et al [12].…”

Clinical evidence of abscopal effect in cutaneous squamous cell carcinoma treated with diffusing alpha emitters radiation therapy: a case report

“…These evidences will further support recent findings on radiation used as immunological adjuvant in numerous clinical scenarios, also in advanced stage diseases [41,42]. Finally, DaRT technique is not complex; however, is still relatively new and requires standardization and specific training as other brachytherapy technique [43,44,45,46].…”

BIT-ART: Multicentric Comparison of HDR-brachytherapy, Intensity-modulated Radiotherapy and Tomotherapy for Advanced Radiotherapy in Prostate Cancer

“…Our results confirmed the feasibility and safety of HDR boost escalation as shown in literature in other patient settings (43)(44)(45); even if HDR has to be performed in specialized centers collecting high numbers of patients with Expert Interventional Radiation Oncologist (46,47).…”

Analysis of local recurrence causes in uveal melanoma patients treated with 125I brachytherapy – a single institution study

“…Ophthalmologists skilled in plaque placement surgery, the radiation oncologist and medical physicists were involved in the treatment procedure, making up a multidisciplinary ocular tumour team. The course of the treatment and follow-up were very similar to that described by Tagliaferri et al [12].…”

Clinical evidence of abscopal effect in cutaneous squamous cell carcinoma treated with diffusing alpha emitters radiation therapy: a case report

“…These evidences will further support recent findings on radiation used as immunological adjuvant in numerous clinical scenarios, also in advanced stage diseases [41,42]. Finally, DaRT technique is not complex; however, is still relatively new and requires standardization and specific training as other brachytherapy technique [43,44,45,46].…”