“…the Na+-K* pump was most sensitive to Ca2+ depletion at pH 8.0. Discussion pH-sensitive K+ channels have been de scribed in various cell types: in retinal pig ment epithelial cells [15], pancreatic B cells [2], mouse astrocytes [31], mammalian kid ney cells [6,11], and in cells of amphibian diluting segment [7,13,17,23,27,32], Fur thermore, data have been published on the pH sensitivity of the Na+-K+-ATPase [14,26,31,32], The results of our experiments are consistent with these studies. Although the intracellular pH has not been evaluated in our study, we assume that changes in extracellular pH are modifying, to some ex tent, the cytoplasmic pH [15,31,32).…”