Interactions of optic radiation lesions with retinal and brain atrophy in early multiple sclerosis
Ting‐Yi Lin,
Claudia Chien,
Joseph Kuchling
et al.
Abstract:ObjectiveRetrograde trans‐synaptic neuroaxonal degeneration is considered a key pathological factor of subclinical retinal neuroaxonal damage in multiple sclerosis (MS). We aim to evaluate the longitudinal association of optic radiation (OR) lesion activity with retinal neuroaxonal damage and its role in correlations between retinal and brain atrophy in people with clinically isolated syndrome and early MS (pweMS).MethodsEighty‐five pweMS were retrospectively screened from a prospective cohort (Berlin CIS coho… Show more
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