“…The lack of any significant increase in HBF with injection of 40 mM-[K+] solution in our experiments, and the direct evidence of pial arteriole constriction in the presence of a high perivascular [K+] (Betz et al 1975) would support the view that blood vessels in the brain respond similarly to those in skeletal muscle in response to local changes in [K+]; that is, by vasodilatation up to a certain perivascular [K+], and by vasoconstriction on further increase in [K+].…”
“…The lack of any significant increase in HBF with injection of 40 mM-[K+] solution in our experiments, and the direct evidence of pial arteriole constriction in the presence of a high perivascular [K+] (Betz et al 1975) would support the view that blood vessels in the brain respond similarly to those in skeletal muscle in response to local changes in [K+]; that is, by vasodilatation up to a certain perivascular [K+], and by vasoconstriction on further increase in [K+].…”
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