1984
DOI: 10.1128/mmbr.48.4.299-325.1984
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Interactions of bacteriophage and host macromolecules in the growth of bacteriophage lambda.

Abstract: The problem of lysogenization is complicated by the fact that the bacterial response does not depend solely on the genetic constitution of the phage and of the bacterium as such, but on the interrelation or interaction of genetic materials." Andre Lwoff (167).

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Cited by 138 publications
(64 citation statements)
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References 167 publications
(235 reference statements)
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“…In addition, nutritional deprivation of the host cells promotes the lysogenic response. However, ifthe viability ofthe lysogenic cell is threatened, the phage is induced into the lytic pathway (Friedman et al, 1984).…”
Section: Discussionmentioning
confidence: 99%
“…In addition, nutritional deprivation of the host cells promotes the lysogenic response. However, ifthe viability ofthe lysogenic cell is threatened, the phage is induced into the lytic pathway (Friedman et al, 1984).…”
Section: Discussionmentioning
confidence: 99%
“…Although not as common as targeting the transcription machinery, increasing evidence shows that some phages also directly target the host replication machinery. While many lytic phages encode most of the proteins for their genome replication, temperate phages as well as some lytic phages depend heavily upon the host replication machinery (Friedman et al, 1984). Through bacteriophage-host interactions, host proteins are recruited for the replication of the bacteriophage genome, often causing the abolition of host replication.…”
Section: Bacteriophage-host Interactions Influencing Replication Of Tmentioning
confidence: 99%
“…The studies of bacteriophage A/Escherichia coli genetic interactions were initiated in the early 1970s and resulted in the identification of a variety of bacterial host functions, which turned out to be of fundamental biological importance (reviewed in detail in [1,2]).…”
Section: Introductionmentioning
confidence: 99%
“…The start point of all these studies was the isolation of E. coil mutants that could not propagate bacteriophage A and the characterization of the cot-nally identified as functions essential for A DNA replication [1,2]. The groEL and groES genes (whose gene products form the GroEL chaperone machine; see below) were originaUy shown to be indispensable for the head morphogenesis of bacteriophage A [1,2].…”
Section: Introductionmentioning
confidence: 99%
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