Abstract:The RNA world hypothesis suggests that RNA systems were the first form of life on the planet, beginning to appear approximately 4 billion years ago. Group I introns are self-splicing RNA elements in extant organisms and use Mg 2+ as the principle divalent cation to promote catalysis. The group I intron ribozyme from Azoarcus is frequently used in origin of life studies, partially due to its autocatalytic abilities-the Azoarcus ribozyme is able to be broken into fragments and reassemble itself into its fully fu… Show more
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