Interactions between single-walled carbon nanotubes and lysozyme

Bomboi, Francesca; Bonincontro, A.; Mesa, Camillo La; Tardani, Franco

doi:10.1016/j.jcis.2010.12.026

Cited by 38 publications

(30 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Comparison of the trends of the two complexes and of the free lysozyme shows that lysozyme retains its native conformation also upon attachment to the CNT and that the conformational change in the CNT 1–lysozyme complex does not involve the secondary structures. The data confirm the experimental evidence that the secondary structure, as well as the majority of the tertiary structure, remain intact when lysozyme is adsorbed onto nanotubes32, 34, 35 and that only random coils and loop structures are affected by the adsorption process 27. The result is potentially interesting for practical applications of these bioconjugates.…”

Section: Resultssupporting

confidence: 82%

“…Additionally, an enhancement in stability for the conjugates was observed in guanidine hydrochloride and under thermal denaturation conditions, thereby indicating stabilization of the conjugate relative to its solution counterpart 34. Circular dichroism (CD)32, 35 measurements confirmed that the secondary structure, as well as the majority of the tertiary structure, remains intact when lysozyme is adsorbed onto nanotubes.…”

Section: Introductionmentioning

confidence: 99%

“…There is a strong fundamental interest in the lysozyme-CNT interaction because lysozyme was one of the first proteins used to solvate CNT. [32,33] The effects of the adsorption of lysozyme are well known [34,35] and novel applications, such as diameter-selective dispersion of CNTs, [36] are being developed. The importance of lysozyme lies also on its extensive use as a model system to understand the underlying principles of protein structure, function, dynamics, and folding.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Probing the Structure of Lysozyme–Carbon‐Nanotube Hybrids with Molecular Dynamics

Calvaresi¹,

Hoefinger²,

Zerbetto³

2012

Chemistry A European J

108

View full text Add to dashboard Cite

Lysozyme has been successfully used to solvate carbon nanotubes (CNT). Extensive molecular dynamics simulations show that 1) a favorite site of adsorption exists, 2) the protein-tube interaction region is located far from the active site, 3) two protein helices act as a tweezer that grips the nanotube, 4) a localized protein re-arrangement hides the tube from the solvent, and 5) aminic and amidic moieties of lysozyme behave similarly to surfactants in the solvation of the tube.

show abstract

Section: Resultssupporting

confidence: 82%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Probing the Structure of Lysozyme–Carbon‐Nanotube Hybrids with Molecular Dynamics

Calvaresi¹,

Hoefinger²,

Zerbetto³

2012

Chemistry A European J

108

View full text Add to dashboard Cite

show abstract

“…More detailed information is given in the original papers, to which the reader is referred. See, in particular [13,31,47,56,58,59,65,66].…”

Section: Appendixmentioning

confidence: 99%

Dispersability of Carbon Nanotubes in Biopolymer-Based Fluids

Tardani

Mesa

2015

Crystals

View full text Add to dashboard Cite

Abstract:In this review the dispersability of carbon nanotubes in aqueous solutions containing proteins, or nucleic acids, is discussed. Data reported previously are complemented by unpublished ones. In the mentioned nanotube-based systems several different phases are observed, depending on the type and concentration of biopolymer, as well as the amount of dispersed nanotubes. The phase behavior depends on how much biopolymers are adsorbing, and, naturally, on the molecular details of the adsorbents. Proper modulation of nanotube/biopolymer interactions helps switching between repulsive and attractive regimes. Dispersion or phase separation take place, respectively, and the formation of liquid crystalline phases or gels may prevail with respect to dispersions. We report on systems containing ss-DNA-and lysozyme-stabilized nanotubes, representative of different organization modes. In the former case, ss-DNA rolls around CNTs and ensures complete coverage. Conversely, proteins randomly and non-cooperatively adsorb onto nanotubes. The two functionalization mechanisms are significantly different. A fine-tuning of temperature, added polymer, pH, and/or ionic strength conditions induces the formation of a given supra-molecular organization mode. The biopolymer physico-chemical properties are relevant to induce the formation of different phases made of carbon nanotubes.

show abstract

“…Liquid crystal phases formed by CNT themselves can improve the quality of carbon nanotubes fibers [9]. It is possible to use LAF solution for stabilization of CNT dispersions and for fabrication protein/CNT conjugates, multifunctional conductive coatings for electronic devices or biocompatible sensors and mechanically strong antibacterial films [10,11]. LAF and CNT are certainly very different materials, but both consist of highly anisotropic molecules.…”

Section: Introductionmentioning

confidence: 99%

Lysozyme Amyloid Fibrils Doped by Carbon Nanotubes

et al. 2018

View full text Add to dashboard Cite

Production of new composites for the creation of modern materials with desired properties is the key feature of nanotechnology. Despite the well known advantages of magnetic nanoparticles, the aim of the present study was to synthesize lysozyme amyloid fibrils from hen egg white and subsequently doped this solution with single walled carbon nanotubes and with the magnetite Fe3O4 labelled single walled carbon nanotubes. Transmission electron microscopy and polarization optical microscopy were used to obtain the structural and dimensional information about samples. Measurements of magnetic properties indicate the considerable increase of the saturation magnetization for solutions included the magnetite nanoparticles.

show abstract

Interactions between single-walled carbon nanotubes and lysozyme

Cited by 38 publications

References 41 publications

Probing the Structure of Lysozyme–Carbon‐Nanotube Hybrids with Molecular Dynamics

Probing the Structure of Lysozyme–Carbon‐Nanotube Hybrids with Molecular Dynamics

Dispersability of Carbon Nanotubes in Biopolymer-Based Fluids

Lysozyme Amyloid Fibrils Doped by Carbon Nanotubes

Contact Info

Product

Resources

About