Interaction of solid supported thin lipid films with saponin

Karabaliev, Miroslav; Kochev, Valery

doi:10.1016/s0925-4005(02)00311-8

Cited by 20 publications

(9 citation statements)

References 23 publications

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“…Sapindus saponaria L. molluscicidal activity is attributed to the presence of saponins (Pinto et al, 1944), substances that interact with sterols present in cell walls of gills mollusks, causing cell rupture (Karabaliev et al, 2003;San Matins et al, 2009) (WHO, 1983b). (Quijano et al, 2014).…”

Section: Resultsmentioning

confidence: 99%

Field Evaluation of Plants Molluscicide against Pomacea canaliculata

Quijano-Avilés

Lara

Riera-Ruiz

et al. 2016

Emir. J. Food Agric

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Section: Resultsmentioning

confidence: 99%

Field Evaluation of Plants Molluscicide against Pomacea canaliculata

Quijano-Avilés

Lara

Riera-Ruiz

et al. 2016

Emir. J. Food Agric

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“…However, the toxicity found, despite the variety of secondary metabolites may be attributed to the synergism which enhances one of the classes present in the extract as saponins. Associated to this class, hemolysis processes which occur by the affinity of the aglycone (steroidal or triterpene nucleus) with cholesterol in cell membranes (Karabaliev and Kochev, 2003), and the hydrophilic moiety composed of one or more chain sugars within the cell acts by inhibiting the enzymatic action of amino acid residues by polar region (Simões et al, 2010).…”

Section: Discussionmentioning

confidence: 99%

Toxicity and phytochemistry of eight species used in the traditional medicine of sul-mato-grossense, Brazil

et al. 2020

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The Brazilian Cerrado has several botanical species for medicinal purposes used by traditional communities and many of these plants are not included in the list of Medicinal Plants Research Program of Central Medicines. The purpose of this study was the phytochemical screening and toxicology bioassay front of Brine shrimp L. of ethanolic extracts of eight species of plants used in folk medicine of Campo Grande, Mato Grosso do Sul, Brazil. The ethanolic extracts were submitted to phytochemical screening, determination of phenolic compounds and flavonoids. Toxicological assays were carried front of Brine shrimp according to standard methodology. The analysis TLC and HPLC-DAD confirmed the predominance of phenolic compounds and derivatives, specifically for the quercetin. The most toxic was the C. affinis DC. with death at all concentrations, the A. humile A. St. Hil. showed no mortality and the other species showed intermediate toxicity. The extracts of the investigated species are rich in phenolic compounds and derivatives, specifically quercetin, and feature toxicity between moderate to high, a fact that requires attention, since much of the traditional communities rely on herbal drugs in its raw form with preventive and curative purpose, meeting the basic health care.

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“…They are substances that have an amphipathic structure formed by hydrophilic sugar residues bonded to a hydrophobic aglycone. In general, these metabolites present the ability to interact with sterols, which are present in the plasmatic membrane of cells, thus allowing ions and water to enter the cell and resulting in cell rupture, which releases hemoglobin 8 . Although the hemolytic properties are an outstanding characteristic of saponins, it is not common to all saponins and this is why the structural definition of aglycone in these compounds is a way of determining this trait 9 .…”

Section: Discussionmentioning

confidence: 99%

EVALUATION OF THE MOLLUSCICIDAL POTENTIAL OF HYDROALCOHOLIC EXTRACTS OF Jatropha gossypiifolia Linnaeus, 1753 ON Biomphalaria glabrata (Say, 1818)

Filho¹,

França²,

Oliveira³

et al. 2014

Rev. Inst. Med. trop. S. Paulo

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The action of extracts from the stem, leaves, and fruit of Jatropha gossypiifolia on Biomphalaria glabrata was studied by analyzing survival, feeding capacity and oviposition ability. The extracts were obtained by macerating the plant parts in 92% ethanol, which were then evaporated until a dry residue was obtained and phytochemically studied. The molluscicidal activity on B. glabrata was investigated using the procedures recommended by WHO (1965). The amount of food ingested and oviposition were measured during each experiment. The extract of leaves from J. gossypiifolia was shown to be a strong molluscicidal agent, causing 100% mortality of B. glabrata, even in the lowest concentration tested, of 25 ppm. Regarding the fruit extract, there was variation in the mortality, depending on the concentration used (100, 75, 50 and 25 ppm). The snails that were in contact with the fruit extract had significant reduction in feeding and number of embryos in comparison to the control. The stem extract did not present molluscicidal activity nor had any influence on the feeding and oviposition abilities of B. glabrata, in the concentrations tested. In conclusion, the extracts of leaves and fruits of J. gossypiifolia investigated in this work show molluscicidal effect and may be sources of useful compounds for the schistosomiasis control.

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Interaction of solid supported thin lipid films with saponin

Cited by 20 publications

References 23 publications

Field Evaluation of Plants Molluscicide against Pomacea canaliculata

Field Evaluation of Plants Molluscicide against Pomacea canaliculata

Toxicity and phytochemistry of eight species used in the traditional medicine of sul-mato-grossense, Brazil

EVALUATION OF THE MOLLUSCICIDAL POTENTIAL OF HYDROALCOHOLIC EXTRACTS OF Jatropha gossypiifolia Linnaeus, 1753 ON Biomphalaria glabrata (Say, 1818)

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