Interaction of receptive field responses and shift-effect in cat retinal and geniculate neurons

Fischer, Burkhart; Barth, R.; Sternheim, Charles E.

doi:10.1007/bf00237602

Cited by 17 publications

(10 citation statements)

References 26 publications

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“…Although Y cells in the lateral geniculate nucleus did have a prominent shift effect, we found little evidence for interaction between peripheral stimuli and stimuli delivered to the receptive field in either X or Y cells. However, in a study simultaneous with ours, Fischer, Barth & Sternheim (1978) 361 362 A. M. DERRINGTON AND A. F. FUCHS also presented shift effect stimuli at different times relative to adequate stimuli delivered to the receptive field. In no identified cells in layers A andAl did the responses to the two stimuli interfere, and in only 3/11 cells was there partial rather than complete summation of the responses (their Fig.…”

Section: Properties Of X and Y Neuroses In The Lateral Geniculate Nucmentioning

confidence: 48%

“…Although Y cells in the lateral geniculate nucleus did have a prominent shift effect, we found little evidence for interaction between peripheral stimuli and stimuli delivered to the receptive field in either X or Y cells. However, in a study simultaneous with ours, Fischer, Barth & Sternheim (1978) Ikeda & Wright (1976) and Cleland et al (1971). Rather than measuring corner frequency, other authors (Ikeda & Wright, 1976;Hoffinann & Sireteanu, 1977) (1971) found that responses of lateral geniculate neurones were less sustained than retinal responses, and that several other properties had to be examined before a cell could be conclusively classified as either sustained or transient.…”

Section: Properties Of X and Y Neuroses In The Lateral Geniculate Nucmentioning

confidence: 92%

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Spatial and temporal properties of X and Y cells in the cat lateral geniculate nucleus.

Derrington¹,

Fuchs²

1979

The Journal of Physiology

121

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SUMMARY1. Extracellular recordings were obtained from units in the dorsal lateral geniculate nucleus of anaesthetized cats.2. Of sixty-nine units, sixty-three could be unambiguously identified as either X (n = 33) or Y (n = 30) by testing the presence of a null response to stationary sine wave gratings presented in different spatial phases.3. In response to stationary gratings flashed on and off, Y cells exhibited bigger, more transient responses than X cells.4. All Y cells but few X cells exhibited a shift effect (modulated periphery effect).5. In response to drifting sine wave gratings of different spatial frequencies, X cells preferred higher spatial frequencies and showed smaller peak contrast sensitivities and somewhat narrower tuning curves than Y cells.6. In response to a sine wave grating of optimal spatial frequency drifting at different velocities, X and Y cells had similar temporal tuning curves. However, Y cells, largely because they preferred lower spatial frequencies, preferred higher drift velocities than X cells.7. Our data suggest that X and Y cells can be differentiated objectively on the basis of a number of discharge parameters. These parameters are compared with similar data collected by others from neurones in the visual cortex.

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Section: Properties Of X and Y Neuroses In The Lateral Geniculate Nucmentioning

confidence: 48%

“…Although Y cells in the lateral geniculate nucleus did have a prominent shift effect, we found little evidence for interaction between peripheral stimuli and stimuli delivered to the receptive field in either X or Y cells. However, in a study simultaneous with ours, Fischer, Barth & Sternheim (1978) Ikeda & Wright (1976) and Cleland et al (1971). Rather than measuring corner frequency, other authors (Ikeda & Wright, 1976;Hoffinann & Sireteanu, 1977) (1971) found that responses of lateral geniculate neurones were less sustained than retinal responses, and that several other properties had to be examined before a cell could be conclusively classified as either sustained or transient.…”

Section: Properties Of X and Y Neuroses In The Lateral Geniculate Nucmentioning

confidence: 92%

Spatial and temporal properties of X and Y cells in the cat lateral geniculate nucleus.

Derrington¹,

Fuchs²

1979

The Journal of Physiology

121

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“…We have checked that, on its own, the shift also increases the firing rate of the majority of retinal ganglion cells. We are testing a number of possible explanations for the difference in effect between the shift stimuli used in our experiments and the shift stimuli used in previous papers (Fischer et al, 1978;Derrington et al, 1979).…”

Section: Discussionmentioning

confidence: 99%

Peripheral shift reduces visual sensitivity in cat geniculate neurones

Derrington

Felisberti

1998

Vis Neurosci

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The sudden displacement of the retinal image during a saccade raises the visual threshold of human observers to foveal stimuli. The fall in visual sensitivity observed during this phenomenon, known as saccadic suppression, seems to occur very early in the visual processing chain. The lateral geniculate nucleus (LGN) is a likely locus for the multiple retinal and extraretinal interactions occurring during saccadic eye movements, therefore we used the responses of relay cells of adult cats to simulate a pychophysical experiment. We first measured the responses of X and Y relay cells (27 X and 13 Y) to central spots of optimal size and different contrasts. The spots were presented either alone or time locked with the rapid movement of a large, high-contrast peripheral pattern, referred to as shift. We measured the percentage of trials on which the relay cell fired more spikes when the spot (contrast: 0.03-1.0) was present than when it was absent. In experiments with human observers the task was to indicate, by a keypress, which of two otherwise identical temporal intervals contained the spot. The shift reduces the sensitivity (raises the contrast threshold) of neurones in the cat relay cells to brief, stationary targets presented to the receptive-field center. The suppression of visual sensitivity is significantly greater in Y cells than in X cells (average sensitivity ratios 5.6 6 5.4 in Y cells, 1.59 6 0.9 in X cells: P Ͻ 0.001, U test). The shift also reduces the sensitivity of human observers to the same target. This suggests that the LGN is a potential locus for the modulation of visual responses that leads to saccadic suppression.

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“…The retinal shift effect, elicited by stimulation outside the conventional receptive field, is of excitatory nature (Mcllwain, 1964;Fischer, Kruger & Droll, 1975;Fischer, Barth & Sternheim, 1978). Similar excitatory responses are observed in cells of the dorsal lateral geniculate nucleus (d.l.g.n.)…”

Section: Introductionmentioning

confidence: 91%

“…Similar excitatory responses are observed in cells of the dorsal lateral geniculate nucleus (d.l.g.n.) following rapid displacements of patterns in the peripheral visual field, but with appropriate steady illumination of the receptive field, decreases in activity are found as well (Fischer & Kruger, 1974;Fischer et al 1978). Differences present between X-and Y-cell shift effects in the retina (Hamasaki & Hanada 1983; equal peak rates but larger shift-response amplitudes in Y than in X cells) are more pronounced in d.l.g.n.…”

Section: Introductionmentioning

confidence: 96%

Contributions of inhibitory mechanisms to the shift responses of X and Y cells in the cat lateral geniculate nucleus.

Eysel

Pape

Schayck

1987

The Journal of Physiology

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SUMMARY1. Adult cats were anaesthetized with a mixture of halothane, nitrous oxide and oxygen to record from single neurones of the dorsal lateral geniculate nucleus (d.l.g.n.) with five-barrel glass micro-electrodes. Periphery effects (shift effects) were elicited by large-field phase-reversing gratings presented in the visual field outside the conventional receptive field area.2. A range of transient excitatory responses was found in X and Y cells. Y cells had phasic shift effects with significantly higher amplitudes and shorter durations (mean 52 impulses/s, 135 ms) than those observed in the tonic shift effects of X cells (mean 24 impulses/s, 169 ms). All Y cells and most X cells responded to stimulation of remote retinal regions. About 7 0 of the X cells displayed no shift effect.3. Micro-ionophoresis of the y-aminobutyric acid (GABA) antagonist bicuculline, acetylcholine (ACh) and L-glutamate specifically influenced the shift effects of X and Y cells.4. During continuous application of the GABA antagonist bicuculline the differences in maximal response rates and amplitudes of X and Y cells were eliminated. The maintained activity raised predominantly in X cells and the early peak rates increased more in X-than in Y-cell shift effects, leading to equal average peak rates of 100 and response amplitudes of about 85 impulses/s in both cell classes. The characteristic time courses of X-and Y-cell responses were not affected.5. Micro-ionophoretic application of ACh caused a combination of excitatory and disinhibitory effects. Maintained activity as well as early parts of stimulus-evoked responses were similarly raised in X and Y cells. In addition, the Y-cell shift effects became less phasic by elevation of the late response part. Sodium pentobarbitone, used to block ACh excitation, suppressed the ACh-induced effects in the early phase of the X-and Y-cell shift effects and the increase of maintained activity in Y-cells, while the effect on the late part of Y-cell responses persisted. Elevation of background activity partially remained in X cells, and the X-cell responses became tonically prolonged at the same time.6. L-Glutamate increased the activity of X and Y cells without changing the characteristic shift-effect properties of both cell classes.

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Interaction of receptive field responses and shift-effect in cat retinal and geniculate neurons

Cited by 17 publications

References 26 publications

Spatial and temporal properties of X and Y cells in the cat lateral geniculate nucleus.

Spatial and temporal properties of X and Y cells in the cat lateral geniculate nucleus.

Peripheral shift reduces visual sensitivity in cat geniculate neurones

Contributions of inhibitory mechanisms to the shift responses of X and Y cells in the cat lateral geniculate nucleus.

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