Interaction of Ninhydrin With N-Hydroxyurea and N-Alkoxyureas in Acetic Acid

Abstract

We have found that ninhydrin reacted with N-hydroxyurea and N-alkoxyureas in acetic acid with the predominant formation of diastereomers of 1,3a,8a-trihydroxy-1,3,3a,8a-tetrahydroindeno[1,2-d]imidazole-2,8-dione and 1-alkoxy-3a,8a-dihydroxy-1,3,3a,8atetrahydroindeno[1,2-d]imidazole-2,8-diones, respectively. with sic-orientation of 3a,8a-HO-groups. The X-ray structural analysis of 1,3aS,8aR-trihydroxy-1,3,3a,8a-tetrahydroindeno[1,2-d]imidazole-2,8-dione and 1-n-butyloxy-3aS,8aR-dihydroxy-1,3,3a,8a-tetrahydroindeno[1,2-d]imidazole-2,8-dione has demonstrated their specific structural features.

Взаємодія 4-Галогенофенілгліоксалей З N-Алкокси-N’-Арилсечовинами

“…We are deeply convinced that N-hydroxyhydantoins and Nalkoxyhydantoins may bring a huge practical value in the field of pharmaceutical and medical industries as well. Our recent research in the arylglyoxals [10] has shown a completely new way to receive the N-hydroxyhydantoins [11][12][13][14] and N-alkoxyhydantoins [12][13][14][15][16][17][18][19][20][21]. We would like to continue discussing these research results in this article.…”

“…1 H NMR spectra were recorded on a VARIAN VNMRS 400 spectrometer (400 MHz). 13 C NMR spectra were recorded ona VARIAN VNMRS 400 spectrometer (100 MHz). The solvent DMSO-d6 was used.…”

“…1 H NMR chemical shifts relative to the residual solvent protons as an internal standard [(CD3)2SO: 2.500 ppm] were reported. Solvent carbon atoms served as an internal standard for 13 C NMR spectra [(CD3)2SO: 39.52 ppm; CDCl3 77.16 ppm]. Mass spectra were recorded on a VG 70-70EQ mass spectrometer in fast atom bombardment mode (FAB).…”

“…Then the aqueous extract was eliminated, the residue was dried under vacuum (2 mmHg) yielding 140 mg of white amorphous solid. According to 1 13 4-Chlorophenylglyoxal interaction with Nethoxy-N'-phenylurea. B. Chlorophenylglyoxal hydrate (107 mg, 0.573 mmol) was dissolved in the solution of N-ethoxy-N'-phenylurea (94 mg, 0.522 mmol) [16; 17] in acetic acid (5 ml).…”

Investigation of Effective Parameters Ce and Zr in the Synthesis of H-ZSM-5 and SAPO-34 on the Production of Light Olefins from Naphtha

“…e addition of Si +4 with P +5 results in the formation of Bronsted acid sites, which makes these molecules more selective as catalyst for specific reaction [55][56][57][58][59][60][61][62][63][64][65][66][67]. Among the various SAPOs, SAPO-34 has a good selectivity to ethylene and propylene.…”