Interaction of lncRNA Gm2044 and EEF2 promotes estradiol synthesis in ovarian follicular granulosa cells
Ke Hu,
Chen Wang,
Yifan Xu
et al.
Abstract:The functions and molecular mechanisms of long noncoding RNA (lncRNA) in reproduction have been widely studied at present. However, lncRNA regulating hormone synthesis in ovarian follicular granulosa cells has not been sufficiently studied. Our previous research demonstrated that lncRNA Gm2044 could promote estradiol synthesis in follicular granulosa cells. In this study, we identified 21 binding proteins of lncRNA Gm2044 in ovarian follicles using comprehensive identification of RNA-binding proteins by mass s… Show more
“…Another study focuses on a crucial yet understudied aspect of long noncoding RNA (lncRNA) function in reproductive biology – its role in regulating hormone synthesis in ovarian follicular granulosa cells [ 19 ]. By narrowing down this area of research, the study fills an important gap in our understanding of reproductive mechanisms.…”
“…Another study focuses on a crucial yet understudied aspect of long noncoding RNA (lncRNA) function in reproductive biology – its role in regulating hormone synthesis in ovarian follicular granulosa cells [ 19 ]. By narrowing down this area of research, the study fills an important gap in our understanding of reproductive mechanisms.…”
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