Interaction of “chromatic” and “achromatic” circuits in Drosophila color opponent processing

Pagni, Manuel; Haikala, Väinö; Oberhauser, Vitus; Meyer, Patrik B.; Reiff, Dierk F.; Schnaitmann, Christopher

doi:10.1016/j.cub.2021.01.105

Cited by 24 publications

(37 citation statements)

References 82 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We have additionally identified as pale-specific the aMe12 and ML-VPN1 cell types, and the yellow bias of Tm5c and the pale bias of Mi9 (Figure 11Bii). Our detailed analysis of Dm8 inputs confirmed that these neurons receive most of their photoreceptor input in a central home column, consistent with pale and yellow subtypes of Dm8 cells having distinct chromatic properties (Courgeon and Desplan 2019, Menon et al 2019, Li et al 2021, Pagni et al 2021. The selective photoreceptor input to these cell types, combined with input to columnar cells from a single photoreceptor subtype, indicate that wavelengthspecific information is maintained in the medulla and lobula (Figure 11Bi).…”

Section: Newly Identified Targets Of Central Versus Dra Inner Photoreceptorssupporting

confidence: 81%

“…Other cell types also received inner photoreceptor input outside the medulla, notably the lamina monopolar cells L1 and L3. These lamina connections indicate that chromatic comparisons arising from R7 and R8 may feed into the motion vision pathway, and identifies a new site for interplay between the 'color' and 'motion' pathways (Wardill et al 2012;Schnaitmann et al 2013;Pagni et al 2021;Li et al 2021). Together, these observations suggest that synapses in an unexpected location, outside the main synaptic layers of the medulla, could play a significant role in early visual processing.…”

Section: Inner Photoreceptor Connections Outside the Medulla Neuropilmentioning

confidence: 95%

See 1 more Smart Citation

Synaptic targets of photoreceptors specialized to detect color and skylight polarization in Drosophila

Kind

Longden

Nern

et al. 2021

eLife

View full text Add to dashboard Cite

Color and polarization provide complementary information about the world and are detected by specialized photoreceptors. However, the downstream neural circuits that process these distinct modalities are incompletely understood in any animal. Using electron microscopy, we have systematically reconstructed the synaptic targets of the photoreceptors specialized to detect color and skylight polarization in Drosophila, and we have used light microscopy to confirm many of our findings. We identified known and novel downstream targets that are selective for different wavelengths or polarized light, and followed their projections to other areas in the optic lobes and the central brain. Our results revealed many synapses along the photoreceptor axons between brain regions, new pathways in the optic lobes, and spatially segregated projections to central brain regions. Strikingly, photoreceptors in the polarization-sensitive dorsal rim area target fewer cell types, and lack strong connections to the lobula, a neuropil involved in color processing. Our reconstruction identifies shared wiring and modality-specific specializations for color and polarization vision, and provides a comprehensive view of the first steps of the pathways processing color and polarized light inputs.

show abstract

Section: Newly Identified Targets Of Central Versus Dra Inner Photoreceptorssupporting

confidence: 81%

Section: Inner Photoreceptor Connections Outside the Medulla Neuropilmentioning

confidence: 95%

Synaptic targets of photoreceptors specialized to detect color and skylight polarization in Drosophila

Kind

Longden

Nern

et al. 2021

eLife

View full text Add to dashboard Cite

show abstract

“…We have additionally identified as pale-specific the aMe12 and ML-VPN1 cell types, and the yellow bias of Tm5c and the pale bias of Mi9 (Figure 11Bii). Our detailed analysis of Dm8 inputs confirmed that these neurons receive most of their photoreceptor input in a central home column, consistent with pale and yellow subtypes of Dm8 cells having distinct chromatic properties (Courgeon and Desplan 2019, Menon et al 2019, Li et al 2021, Pagni et al 2021). The selective photoreceptor input to these cell types, combined with input to columnar cells from a single photoreceptor subtype, indicate that wavelength-specific information is maintained in the medulla and lobula (Figure 11Bi).…”

Section: Discussionsupporting

confidence: 81%

“…L3 could contribute to color processing through innervation of Dm9, Tm20, and Tm5c (Takemura et al 2015), in addition to the ON and OFF pathways computing motion (Silies et al 2013). Our reconstructions therefore provide further support for the early convergence of motion and color channels, which have until recently been believed to operate separately (Heisenberg and Buchner 1977; Yamaguchi et al 2008; Wardill et al 2012; Pagni et al 2021; Li et al 2021).…”

Section: Resultssupporting

confidence: 68%

“…Other cell types also received inner photoreceptor input outside the medulla, notably the lamina monopolar cells L1 and L3. These lamina connections indicate that chromatic comparisons arising from R7 and R8 may feed into the motion vision pathway, and identifies a new site for interplay between the ‘color’ and ‘motion’ pathways (Wardill et al 2012; Schnaitmann et al 2013; Pagni et al 2021; Li et al 2021). Together, these observations suggest that synapses in an unexpected location, outside the main synaptic layer of the medulla, could play a significant role in early visual processing.…”

Section: Discussionmentioning

confidence: 97%

See 1 more Smart Citation

Synaptic targets of photoreceptors specialized to detect color and skylight polarization in Drosophila

Kind

Longden

Nern

et al. 2021

Preprint

View full text Add to dashboard Cite

Color and polarization provide complementary information about the world and are detected by specialized photoreceptors. However, the downstream neural circuits that process these distinct modalities are incompletely understood in any animal. We have systematically reconstructed, using light and electron microscopy, the synaptic targets of the photoreceptors specialized to detect color and polarized light in Drosophila. We identified known and novel downstream targets that are selective for different wavelengths as well as for polarized light and followed their projections to other areas in the optic lobes and the central brain. Strikingly, photoreceptors in the polarization-sensitive dorsal rim area target fewer cell types, that lack strong connections to the lobula, a neuropil with a proposed role in color processing. Our reconstruction identifies shared wiring and modality-specific specializations for color and polarization vision, and provides a comprehensive view of the first steps of the pathways processing color and polarized light inputs.

show abstract

Looking across the gap: Understanding the evolution of eyes and vision among insects

Kittelmann,

McGregor

2024

BioEssays

View full text Add to dashboard Cite

The compound eyes of insects exhibit stunning variation in size, structure, and function, which has allowed these animals to use their vision to adapt to a huge range of different environments and lifestyles, and evolve complex behaviors. Much of our knowledge of eye development has been learned from Drosophila, while visual adaptations and behaviors are often more striking and better understood from studies of other insects. However, recent studies in Drosophila and other insects, including bees, beetles, and butterflies, have begun to address this gap by revealing the genetic and developmental bases of differences in eye morphology and key new aspects of compound eye structure and function. Furthermore, technical advances have facilitated the generation of high‐resolution connectomic data from different insect species that enhances our understanding of visual information processing, and the impact of changes in these processes on the evolution of vision and behavior. Here, we review these recent breakthroughs and propose that future integrated research from the development to function of visual systems within and among insect species represents a great opportunity to understand the remarkable diversification of insect eyes and vision.

show abstract

Interaction of “chromatic” and “achromatic” circuits in Drosophila color opponent processing

Cited by 24 publications

References 82 publications

Synaptic targets of photoreceptors specialized to detect color and skylight polarization in Drosophila

Synaptic targets of photoreceptors specialized to detect color and skylight polarization in Drosophila

Synaptic targets of photoreceptors specialized to detect color and skylight polarization in Drosophila

Looking across the gap: Understanding the evolution of eyes and vision among insects

Contact Info

Product

Resources

About