Interaction of antiphospholipid antibodies with endothelial cells in antiphospholipid syndrome
Weimin Feng,
Jiao Qiao,
Yuan Tan
et al.
Abstract:Antiphospholipid syndrome (APS) is an autoimmune disease with arteriovenous thrombosis and recurrent miscarriages as the main clinical manifestations. Due to the complexity of its mechanisms and the diversity of its manifestations, its diagnosis and treatment remain challenging issues. Antiphospholipid antibodies (aPL) not only serve as crucial “biomarkers” in diagnosing APS but also act as the “culprits” of the disease. Endothelial cells (ECs), as one of the core target cells of aPL, bridge the gap between th… Show more
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