Sandwich beams, comprising two stiff facesheets bonded to a core, are light and strong and see widespread application. However, debonded regions between the facesheets and the core can significantly reduce the strength and have an impact on the vibration behaviour. In this study, the previous literature was referred to, and finite element simulations were conducted using ANSYS on debonded sandwich beams with [0°]4, [+45°/−45°]S and [90°]4 carbon fibre reinforced polymer facesheets. The effects of the configurations of the three debonded regions and facesheet stacking orientations were studied. The most important finding is that if debonds cover vibration nodes, the natural frequencies drop more significantly because the stiffness decreases more. It was determined that when there were debonded regions, the natural frequencies of the bending modes of the beams using [0°]4 facesheets decreased more compared to those of the beams using [+45°/−45°]S and [90°]4 facesheets; while the trends are opposite for the natural frequencies of torsion modes of the beams using [+45°/−45°]S facesheets. Reducing the natural frequency can cause a structure to vibrate at the resonance frequency, leading to structural failure. This study contributes to furthering our understanding of how different debonds and facesheet stacking orientations affect the vibrations of sandwich beams.