Interaction between Prenatal and Postnatal Exposure to High-Fructose Corn Syrup Increases Gene Expression of <i>Tnfa</i> in Hippocampus of Offspring
Mirai YAMAZAKI,
Hiroya YAMADA,
Eiji MUNETSUNA
et al.
Abstract:Concerns about the negative intergenerational effects of excessive fructose intake are being raised, with evidence suggesting that prenatal fructose intake increases susceptibility to metabolic and cognitive dysfunction later in life. In the present study, we hypothesized that prenatal and postnatal fructose intake acts synergistically to impact on hippocampus of adult offspring. Female Sprague-Dawley rats received distilled water or 20% high-fructose corn syrup (HFCS) solution in addition to standard chow thr… Show more
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