Interaction Between Opioidergic and Dopaminergic Systems on Food Intake in Neonatal Layer Type Chicken

Zendehdel, Morteza; Ghashghayi, Elham; Hassanpour, Shahin; Baghbanzadeh, Ali; Jonaidi, Hossein

doi:10.1007/s10989-015-9486-4

Cited by 21 publications

(9 citation statements)

References 44 publications

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“…Given the estimated 300 million years of evolutionary distance between mammals and avian, it is not surprising that significant differences have been found in the activity of neurotransmitters such as ghrelin involved in the regulation of energy homeostasis doi: 10.17221/2/2016-CJAS (Novoseletsky et al 2011;Zendehdel et al 2015b). To the best of our knowledge, there has been no previous study on the role of opioid receptors in feeding response of avian species in the presence of different diets.…”

Section: Discussionmentioning

confidence: 99%

Effect of opioid receptors agonists on feeding behaviour using different diets in ad libitum fed neonatal chicken

Zendehdel¹,

Ebrahimnezhad²,

Ghalehkandi³

et al. 2017

CZECH J ANIM SCI

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Arva S., Zendehdel M., EbrahimNezhad Y., Ghiasi Ghalehkandi J., Hassanpour S., Aghdam Shahryar H. (2017): Effect of opioid receptors agonists on feeding behaviour using different diets in ad libitum fed neonatal chicken. Czech J. Anim. Sci., 62, 98-109.Despite progress in studying the role of opioids in reward, the effect of opioid receptors on feeding behaviour in ad libitum fed meat-type chicken offered different diet types is still unclear. So in this study, 12 experiments (each included 4 groups) were designed to determine the role of μ, δ, and κ receptors with different diets on feeding responses in ad libitum fed neonatal chicken. In Experiment 1, group A chicken were intracerebroventricularly (ICV) injected with saline, groups B-D chicken were ICV injected with DAMGO (µ-opioid receptor agonist; 125, 250, and 500 pmol), then standard diet without fat was offered. In Experiment 2, group A chicken were ICV injected with saline, groups B-D chicken were ICV injected with DAMGO (125, 250, and 500 pmol) and diet with nutrient energy ratio 20% below standard was provided to the birds. Experiments 3-4 were similar to Experiment 1, except after injection, diets containing nutrient energy ratio 20% above standard and standard diet with fat were provided to the birds, respectively. In Experiment 5, chicken were ICV injected with saline, DPDPE (δ-opioid receptor agonist) at doses of 20, 40, and 80 nmol, and then received standard diet without fat. Experiments 6-8 were similar to Experiment 5 in which diet containing nutrient energy ratio by 20% lower than standard, diet containing nutrient energy ratio by 20% higher than standard, and diet containing fat were provided instead of standard diet without fat to the birds, respectively. In Experiment 9, birds received ICV injection of saline and U-50488H (κ-opioid receptor agonist; 10, 20, and 40 nmol) and were provided standard diet without fat. Experiments 10-12 were similar to Experiment 9 but after ICV injection, birds were fed diet containing by 20% lower nutrient energy ratio, diet containing by 20% higher nutrient energy ratio, and standard diet containing fat, respectively. Then the cumulative food intake was measured until 180 min post injection. According to the results, DAMGO decreased while DPDPE and U-50488H increased the food intake (P < 0.05). These findings suggest endogenous governing food preferences via δ-and κ-opioid receptor in ad libitum fed neonatal chicken.

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Section: Discussionmentioning

confidence: 99%

Effect of opioid receptors agonists on feeding behaviour using different diets in ad libitum fed neonatal chicken

Zendehdel¹,

Ebrahimnezhad²,

Ghalehkandi³

et al. 2017

CZECH J ANIM SCI

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“…The b adrenergic receptors coupled to adenylate cyclase to stimulate the cAMP signaling pathway while a 1 receptors activation indirectly modulates the b receptors (Roozendaal et al 2008). CRF and its receptors, play crucial effects on energy intake, body weight regulation and known as a hypophagic neurotransmitter (Zendehdel et al 2016). N/OFQ inhibited stress-induced anorexia by blockade of hypothalamic CRF 2 receptors (Ciccocioppo et al 2004).…”

Section: Discussionmentioning

confidence: 99%

“…Only data from individuals in which dye was present in their lateral ventricle were used for analysis. All experimental procedures were done from 8:00 A.M. until 3:30 P.M. Also, the time course of food consumption was selected by previous studies (Jonaidi and Noori 2012;Zendehdel and Hassanpour 2014;Hassanpour et al 2015;Zendehdel et al 2016).…”

Section: Intracerebroventricular Injection Proceduresmentioning

confidence: 99%

Interaction Between Nociceptin/Orphanin FQ and Adrenergic System on Food Intake in Neonatal Chicken

Zendehdel

Parvizi

Hassanpour

et al. 2016

Int J Pept Res Ther

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The information emerging from the studies demonstrates adrenergic system and nociceptin/orphanin FQ (N/OFQ) play a crucial role on appetite regulation but there is no information for their interaction. The purpose of this study was to examine the effects of intracerebroventricular (ICV) injection of prazosin (a 1 receptor antagonist), yohimbine (a 2 receptor antagonist), metoprolol (b 1 adrenergic receptor antagonist), ICI 118,551 (b 2 adrenergic receptor antagonist) and SR59230R (b 3 adrenergic receptor antagonist) on N/OFQ-induced hyperphagia by 3-h fooddeprived neonatal broiler chicken. In experiment 1, chicken injected with saline, prazosin (10 nmol), N/OFQ (16 nmol) and co-injection of prazosin ? N/OFQ. In experiment 2, ICV injection of saline, yohimbine (13 nmol), N/OFQ (16 nmol) and yohimbine ? N/OFQ applied to the birds. In experiment 3, injections were saline, metoprolol (24 nmol), N/OFQ (16 nmol) and metoprolol ? N/OFQ. In experiment 4, the birds received ICV injection of saline, ICI 118,551 (5 nmol), (C) N/OFQ (16 nmol) and co-administration of ICI 118,551 ? N/OFQ. In experiment 5, chicken injected with saline, SR59230R (20 nmol), N/OFQ (16 nmol) and SR59230R ? N/OFQ. Then, cumulative food intake was recorded until 120 min after injection.According to the results, ICV injection of N/OFQ significantly increased food intake (P \ 0.001). The effect of N/OFQ significantly amplified by co-injection of N/OFQ ? b 2 adrenergic receptor antagonist (P \ 0.001). Also, administration of b 1 or b 3 adrenergic receptor antagonist had no effect on N/OFQ-induced hyperphagia (P [ 0.05). These results suggest that the effect of N/OFQ on cumulative food intake is mediated via b 2 adrenergic receptors in neonatal chicken.

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“…Each bird was injected once only. These doses of drugs were calculated based on the previous studies (Bungo et al, 2004(Bungo et al, , 2005Taati et al, 2009;Shojaei et al, 2015;Zendehdel et al, 2015Zendehdel et al, , 2016a and our pilot studies (un-published data). Right away after the injection, chickens were returned to their individual cages and provided ad libitum food (pre-weighed) and water.…”

Section: Feeding Experimentsmentioning

confidence: 99%

“…The intracerebroventricular (ICV) injection of [D-Ala 2 , NMe-Phe 4 , Gly 5 -ol]-enkephalin (DAMGO) and β-casomorphin (µ-opioid receptor agonists) induce hypophagia while [D-Pen 2, 5 ]-enkephalin (DPDPE) (δ-opioid receptor agonist) exerts orexigenic effects in mammals (Kaneko et al, 2012). The ICV injection of µ-opioid receptor agonists induces hypophagia while δ-opioid receptor agonist and U-50488H (κ-opioid receptor agonist) has a hyperphagic effect in neonatal layer and broiler chicks (Bungo et al, 2004;Shiraishi et al, 2008, Shojaei et al, 2015Zendehdel et al, 2016a).…”

Section: Introductionmentioning

confidence: 99%

Central Opioidergic System Interplay with Histamine on Food Intake in Neonatal Chicks: Role of µ-Opioid and H1/H3 Receptors

Jaefari-Anari

Zendehdel

Gilanpour

et al. 2018

Braz. J. Poult. Sci.

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Interaction Between Opioidergic and Dopaminergic Systems on Food Intake in Neonatal Layer Type Chicken

Cited by 21 publications

References 44 publications

Effect of opioid receptors agonists on feeding behaviour using different diets in ad libitum fed neonatal chicken

Effect of opioid receptors agonists on feeding behaviour using different diets in ad libitum fed neonatal chicken

Interaction Between Nociceptin/Orphanin FQ and Adrenergic System on Food Intake in Neonatal Chicken

Central Opioidergic System Interplay with Histamine on Food Intake in Neonatal Chicks: Role of µ-Opioid and H1/H3 Receptors

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