Interaction between nanocluster polyoxometallates and low-molecular-weight organic compounds

Abstract

The equilibrium sorption of methanol and benzene vapors by spherical porous nanocluster polyoxometallates with keplerate structures of different compositions (Mo 132 and Mo 72 Fe 30 ) and polyoxometallate (Mo 138 ) with a toroidal structure and patterns in the kinetics of these processes are studied. Changes in the chemical potentials of the sorbates and polyoxometallates, specific Gibbs energies of the interaction of the polyoxometallates with the indicated substances, and the partial molar entropy of the interaction of Mo 132 with methanol are calculated. The stability of the polyoxometallate structure in the sorbate vapors is studied via IR and Raman spectroscopy.

Physicochemical and biochemical properties of the Keplerate-type nanocluster polyoxomolybdates as promising components for biomedical use

“…In addition, it was shown that simpler molybdenum-containing POMs can be used in chemotherapy [115,116]. On the other hand, the initially predicted possibility of the formation of POM conjugates with bioactive substances, drugs, and metal cations using intra-and extrasphere interactions, the possibility of their transport (including iontophoretic) in the body, adds relevance to the studies of POM in the field of targeted drug delivery and diagnostics [117][118][119][120][121][122][123][124][125][126][127][128][129][130][131]. These prospects may relate, inter alia, to immunomodulatory and antiviral agents.…”

The use of nanocluster polyoxometalates in the bioactive substance delivery systems

“…POM show stability in weakly acidic solutions, and can be isolated in crystalline or amorphized state. Due to the presence of an internal cavity and pores in the structure of Keplerates, it is possible to introduce various substances inside them, both ions and molecules [337,338], including bioactive substances, which makes them promising in the context of creating nanocapsules for targeted drug delivery [339]. Fig.…”