1987
DOI: 10.1016/0378-1097(87)90217-5
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Interaction between fibronectin and purified staphylococcal clumping factor

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Cited by 2 publications
(3 citation statements)
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“…However, in 1954, Duthie (7) suggested that coagulase and clumping factor were separate entities. Since this work was published, there have been several reports claiming to have identified, and in some cases to have purified, clumping factor (6,22,37,39). Recently, Boden and Flock (3,4) showed that coagulase could bind to fibrinogen as well as to prothrombin and that a proportion of the normally extracellular protein was tightly associated with the cell surface.…”
mentioning
confidence: 96%
“…However, in 1954, Duthie (7) suggested that coagulase and clumping factor were separate entities. Since this work was published, there have been several reports claiming to have identified, and in some cases to have purified, clumping factor (6,22,37,39). Recently, Boden and Flock (3,4) showed that coagulase could bind to fibrinogen as well as to prothrombin and that a proportion of the normally extracellular protein was tightly associated with the cell surface.…”
mentioning
confidence: 96%
“…bacterial whole cells by fibronectin shown by Chhatwal et al (2). In order to avoid any nonspecific binding of lgG to staphylococcal protein A, furthermore, the Fc regions were removed from all the antibody preparations in the ELISA forfibrinogen-binding activities.…”
mentioning
confidence: 99%
“…Considering that the staphylococcal clumping factor directly binds to fibrinogen molecules (1)(2)(3)(4)(5)8), absence of such a singificant correlation between expression of these two activities may suggest the following possibilities: (a) the clumping may be a phenomenon in which several factors including the fibrinogen-binding material(s) participate;…”
mentioning
confidence: 99%