Inter-trophic Interaction of Gut Microbiota in a Tripartite System

Yi, Xin; Guo, Jian; Wang, Minghui; Xue, Chunlai; Ju, Mengyao

doi:10.1007/s00248-020-01640-4

Cited by 5 publications

(4 citation statements)

References 102 publications

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“…Molecular variance (Adonis) was analyzed to test the differences in gut microbiota compositions. The statistical significance was set as p < 0.05 [ 30 ]. The relative abundant values of OTUs between antibiotics treatments were detected using algorithm of Linear Discriminant Analysis Effect Size (LEfSe).…”

Section: Methodsmentioning

confidence: 99%

Maternal Gut Dysbiosis Alters Offspring Microbiota and Social Interactions

Zhang

Xue

et al. 2021

Microorganisms

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Increasing application of antibiotics changes the gut microbiota composition, leading to dysbiosis of the gut microbiota. Although growing evidence suggests the potential role of gut dysbiosis as the cause of neurodevelopmental disorders and behavioral defects, a broad gap of knowledge remains to be narrowed to better understand the exact mechanisms by which maternal gut dysbiosis alters microbiota development and social interactions of offspring. Here, we showed that maternal gut dysbiosis during gestation is a critical determinant of gut microbiota and social interactions off mouse offspring. Gut microbiota of 2-week-old offspring showed significant changes in response to maternal antibiotic treatment. We even detected distinct effects of maternal oral antibiotics on gut microbiota of 14-week-old offspring. Compared to controls, offspring born to antibiotics-treated mothers displayed reduction in sociability and preference for social novelty, suggesting that the altered offspring social behavior was closely linked to dysbiosis of maternal gut microbiota. Our study opens the possibility to better understand the mechanism of how maternal gut microbiota vertically impairs social interactions of offspring in animal models, providing support to the maternal gut microbiota as a potential mediator between offspring microbiota and behaviors.

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Section: Methodsmentioning

confidence: 99%

Maternal Gut Dysbiosis Alters Offspring Microbiota and Social Interactions

Zhang

Xue

et al. 2021

Microorganisms

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“…For instance, research has demonstrated that the balance of the gut microbiota plays a crucial role in the sexual selection and reproductive behavior of the host (Walsh et al, 2017). In a study of this Research Topic by Yi et al (2021), it was shown that antibiotic-induced dysbiosis of the gut microbiota in mice reduced the sexual attractiveness of females to males, possibly due to the negative impact of the vertical transmission of dysbiosis of maternal gut microbiota on the immunity and social competence of offspring. Thus, favoring healthy females over those with gut bacteria dysbiosis may facilitate population reproduction (Yi and Cha).…”

Section: Microbial Transmission Shapes Gut Microbiomementioning

confidence: 99%

“…Fu et al (2021) shows that sympatric yaks and pikas on the Tibetan plateau could shift from competition to reciprocity by mutually acquiring beneficial microorganisms through the horizontal transfer of fecal microorganisms. Moreover, chipmunks can acquire beneficial microbes resistant to phytotoxins present in the gut of other insects through the food chain (Yi et al, 2021). Thus, the spread of gut microbiota in animal social networks (intra-or inter-population) warrants additional attention in the future owing to the influence of multiple potential impact mechanisms, such as social behavior (Sarkar et al, 2020), food chains (Moeller et al, 2017) and sympatric species composition (Perofsky et al, 2019;Fu et al, 2021), on animal microbiome transmission.…”

Section: Future Of Animal Social Behavior and Gut Microbiomementioning

confidence: 99%

Editorial: Animal social behaviour and gut microbiome

Zhu

2023

Front. Microbiol.

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“…While the impact of tannins on caterpillar growth, survival, or gut physiology has been extensively studied ( 21 , 25 , 27 , 28 ), the effect on their gut microbiome has been neglected [but see references ( 29 , 30 )]. Significant changes in gut microbiome composition have been reported under tannin exposure in larval insects ( 29 , 31 ) and vertebrates ( 32 ), including humans ( 33 ). To deepen our understanding of the role of tannins in plant–herbivore interactions, manipulative experiments controlling tannin levels are needed, as most studies have relied on correlations ( 34 ).…”

Section: Introductionmentioning

confidence: 99%

Concentration-dependent effect of plant secondary metabolites on bacterial and fungal microbiomes in caterpillar guts

Šigutová,

Pyszko,

Šigut

et al. 2024

Microbiol Spectr

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Plant–herbivore interactions have been modulated by plant secondary metabolites (PSM), which exert a strong pressure on herbivore microbiome. This study examined the effects of different PSM types and concentrations on caterpillar fitness, composition of gut bacterial and fungal assemblages, and microbiome network stability and symbiotic bonds in relation to the caterpillar diet breadth. Polyphagous and monophagous caterpillars sampled from oak were reared on an artificial diet (AD) containing PSM native (tannic acid) and non-native (tannivin and salicylic acid) to oak at varying concentrations, along with control treatments (starving and fed by oak leaves or AD without PSM). Their gut microbiome was profiled using 16S and ITS2 rRNA gene metabarcoding. Contrary to expectations, the diet breadth combined with the PSM type had no effect on weight gain. The bacterial composition was shaped by PSM concentration, while caterpillar species and diet breadth had no effect. Compared with bacteria, concentration had no effect on the fungal composition, which was more influenced by diet breadth than by caterpillar species. Leaf-fed caterpillars harbored the highest microbial richness. In AD-fed caterpillars, bacteria formed more complex networks than fungi, and the complexity was simplified with higher PSM concentrations. We identified taxa significantly associated with caterpillar guts. Notably, the association Lactobacillus–Lactococcus–Streptococcus was universally present across all caterpillar species, regardless of diet breadth. Our findings emphasize the importance of considering PSM concentration and composition in understanding caterpillar–gut microbiome interactions. Further research will validate the functional roles of identified microbial taxa and their significance for caterpillar hosts. IMPORTANCE The caterpillar gut is an excellent model system for studying host–microbiome interactions, as it represents an extreme environment for microbial life that usually has low diversity and considerable variability in community composition. Our study design combines feeding caterpillars on a natural and artificial diet with controlled levels of plant secondary metabolites and uses metabarcoding and quantitative PCR to simultaneously profile bacterial and fungal assemblages, which has never been performed. Moreover, we focus on multiple caterpillar species and consider diet breadth. Contrary to many previous studies, our study suggested the functional importance of certain microbial taxa, especially bacteria, and confirmed the previously proposed lower importance of fungi for caterpillar holobiont. Our study revealed the lack of differences between monophagous and polyphagous species in the responses of microbial assemblages to plant secondary metabolites, suggesting the limited role of the microbiome in the plasticity of the herbivore diet.

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Inter-trophic Interaction of Gut Microbiota in a Tripartite System

Cited by 5 publications

References 102 publications

Maternal Gut Dysbiosis Alters Offspring Microbiota and Social Interactions

Maternal Gut Dysbiosis Alters Offspring Microbiota and Social Interactions

Editorial: Animal social behaviour and gut microbiome

Concentration-dependent effect of plant secondary metabolites on bacterial and fungal microbiomes in caterpillar guts

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