Inter-observer agreement of canine and feline paroxysmal event semiology and classification by veterinary neurology specialists and non-specialists

Packer, Rowena M. A.; Berendt, Mette; Bhatti, Sofie; Charalambous, Marios; Cizinauskas, Sigitas; Risio, Luisa De; Farquhar, Robyn; Hampel, Rachel; Hill, Myfanwy F; Mandigers, Paul J. J.; Pákozdy, Ákos; Preston, Stephanie M.; Rusbridge, Clare; Stein, Veronika M.; Taylor-Brown, Fran; Tipold, Andrea; Volk, Holger A.

doi:10.1186/s12917-015-0356-2

Cited by 38 publications

(39 citation statements)

References 15 publications

(23 reference statements)

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“…Therefore, owners of dogs affected by tetanus should be counseled that RBD/cpRBD could develop and, to assist in diagnosis, video footage should be obtained, and they should establish whether they can wake their pet, if safe to do so. As a previous study has shown a relatively low level of interobserver agreement regarding classification of paroxysmal events in dogs and cats as epileptic seizures or not on the basis of video footage alone, where possible, EEG and polysomnography recording should be obtained during an episode in order to reach a definitive diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Association between clinically probable REM sleep behavior disorder and tetanus in dogs

Shea

Hatch²,

Risio

et al. 2018

Veterinary Internal Medicne

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BackgroundAbnormal sleep behavior has been reported in 5 dogs during recovery from tetanus.HypothesisREM sleep behavior disorder (RBD) is a more common consequence of tetanus than previously reported in veterinary literature and easily confused for epileptic seizures.AnimalsSixty‐one client‐owned dogs diagnosed with tetanus at 2 UK referral centers.MethodsA retrospective review of medical records was combined with a questionnaire sent to owners of surviving dogs, to identify cases that developed clinically probable RBD and determine its clinical progression and effect on quality of life of affected dogs and their owners. Descriptive statistical evaluation was performed.ResultsEleven dogs (18%) died or were euthanized before discharge. At least 46% surviving dogs developed abnormal “dream enactment” clinically consistent with RBD. Twitching, running, and vocalization were new sleep behaviors in 53, 80, and 60% of affected dogs. Clinically probable RBD was described as violent or “nightmare”‐like in 36% affected dogs, and like an epileptic seizure in 40% affected dogs. When trialed, antiepileptic medications were ineffective. Onset occurred before discharge in 25% cases. For dogs that developed clinically probable RBD postdischarge, onset occurred within 2 weeks of discharge in 77% dogs. Clinically probable RBD did not worsen in severity or frequency in any dog, and spontaneously resolved within 6 months in 43% cases.Conclusions and Clinical ImportanceClinically probable RBD is a common sequel to canine tetanus with many clinical similarities to epileptic seizure activity. Owners should be made aware of its potential development and care taken to avoid misdiagnosis with epileptic seizure activity.

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Section: Discussionmentioning

confidence: 99%

Association between clinically probable REM sleep behavior disorder and tetanus in dogs

Shea

Hatch²,

Risio

et al. 2018

Veterinary Internal Medicne

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“…Video recording of the event is highly recommended, as it can be a rather helpful tool. However, a relatively recent study showed that video footage should be interpreted with caution (Packer et al, 2015). Precisely, the study found that there was a low level of agreement among veterinarians who were not always able to interpret, based on the videos, whether they could observe an epileptic seizure or another paroxysmal event.…”

Section: Introductionmentioning

confidence: 64%

Epileptic Seizures Versus Syncope: Pathophysiology and Clinical Approach

Charalambous

Gomes

Papageorgiou³

et al. 2017

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Generalised epileptic seizures and syncope are two syndromes with similar clinical manifestation and their differentiation can be quite challenging. The aim of this review is to use an evidence-based approach in differentiating these two syndromes through the comprehension of the pathophysiological mechanisms involved and their clinical signs. Both syndromes affect regions of the forebrain and consciousness level, although, different mechanisms are involved. Syncope is a paroxysmal event secondary to a short-term decrease in cerebral perfusion, oxygenation or essential nutrients delivery. Generalised epileptic seizure activity is defined as the clinical manifestation of transient paroxysmal disturbances in brain function secondary to an imbalance between excitatory and inhibitory neurotransmitters. Clinical criteria, including precipitating events, clinical signs preceding, during and following the episodes and event duration, can be used to differentiate the two syndromes. Although these criteria might be useful for the practitioner, definite conclusions should be precluded due to the lack of original research articles and weak evidence on this specific field. Application:The review might be a useful tool for the general practitioner and clinical scientist as it will aid towards the differentiation of two syndromes, i.e. generalised epileptic seizures and syncope, with similar clinical presentation.

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“…A recent research study was performed to investigate the level of agreement between veterinarians (both neurologist specialists and non‐specialists) on the description and classification of the videos depicting paroxysmal events, without knowing any results of diagnostics workup ( Packer et al . ). This study highlighted the need for ongoing debate regarding the descriptive terminology used for seizure semiology in veterinary medicine and the need for further training in focused areas.…”

Section: Clinical Manifestations During Seizuresmentioning

confidence: 97%

“…A recent research study was performed to investigate the level of agreement between veterinarians (both neurologist specialists and non-specialists) on the description and classification of the videos depicting paroxysmal events, without knowing any results of diagnostics workup ( Packer et al . 2015 ).…”

Section: Clinical Manifestations During Seizuresmentioning

confidence: 99%

Canine versus human epilepsy: are we up to date?

Uriarte¹,

Saiz

2016

J of Small Animal Practice

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In this paper we analyse and compare features of canine and human epilepsy and we suggest new tools for better future understanding of canine epilepsy. The prevalence of epileptic seizures in dogs ranges between 0.5% and 5.7% and between 1% and 3% in the human population. Studies on human epilepsy provide a ready-made format for classification, diagnosis and treatment in veterinary epilepsy. Human studies highlight the value of a thorough seizure classification. Nevertheless, a matter of concern in canine epilepsy is the limited information regarding seizure description and classification because of the lack of EEG-video recording. Establishment of a consensus protocol for ambulatory home video-recording in dogs who suffer from epilepsy, mainly considering indications, duration of monitoring, the sufficient essential training for an optimal interpretation of ictal semiology and the methodology of recordings is needed. The ultimate goal is that the information gathered by these videos will be analysed to describe the epileptic seizures thoroughly, recognize patterns and move towards a better understanding and therefore classification of canine epileptic seizures.

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Inter-observer agreement of canine and feline paroxysmal event semiology and classification by veterinary neurology specialists and non-specialists

Cited by 38 publications

References 15 publications

Association between clinically probable REM sleep behavior disorder and tetanus in dogs

Association between clinically probable REM sleep behavior disorder and tetanus in dogs

Epileptic Seizures Versus Syncope: Pathophysiology and Clinical Approach

Canine versus human epilepsy: are we up to date?

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