This study aimed to integrate the dimensions and elements of intra-cluster coopetition, identify the emergence of a complementary theoretical perspective to cluster theory and create an integrative research agenda to support the rethinking cluster approach based on coopetition. It is an integrative Systematic Literature Review that generates insights to move the topic forward. Results showed coopetition as context, process, or outcome. The research focus was grouped into six dimensions of intra-cluster coopetition: Strategic Adjustment, Perceived Benefits, Mediated Coopetition, Social Interaction, Coopetitive Orientation, and Temporality of Coopetition. Four hundred eighty-six elements used by scholars created a second-order coding to represent the variables of coopetition in clusters. From the integrative literature overview, a theoretical framework emerges with four dimensions: Conditional factors, Policies, Market commonality, and Formal supporting structure. These dimensions act as drivers, markets, or intensifiers of the intra-cluster coopetition strategy. At the same time, the dimensions suffer the influence of external, internal, and ecosystem contexts. Our literature review builds theory to advance cluster coopetition research and complement the Porterian perspective. The framework suggests the main elements to manage clusters under the coopetition strategy. These findings rethink cluster theory and deliver the business co-evolution perspective, considering the cluster as a business ecosystem with an open system based on coopetition. Findings offer an inductive-deductive pattern system to further research that represents the evolutionary trend of the topic itself.