Intentional Carbofuran Poisoning in 7 dogs

Abstract

Background: Carbofuran was a widely used board-spectrum pesticide, which despite his strict regulation and bans for more than one decade is still encountered in cases of intentional poisoning in dogs and wildlife. The objective of the study was to provide a complete and detailed description of the pathological, histological and toxicological findings of the 7 cases of intentional carbofuran poisoning in dogs.Results: In this retrospective study 7 cases of carbofuran intoxication recorded from July 2015 to June 2017 were analyzed. Following complete history recording, all cases were examined by complete necropsy and histopathology. The carbofuran intoxication was confirmed in all cases by gaschromatography. The postmortem examination revealed extensive haemorrhages and congestion located mainly within the respiratory, nervous and cardiovascular systems, accompanied by degeneration and necrosis within the lung, heart, and kidneys.Conclusions: Although banned in the European Union, carbamate poisoning is still frequently encountered, especially in wild animals. This paper will contribute to a better understanding of occurrence and pathogenesis of acute carbofuran exposure in dogs, and add some peculiar pathological features of this poisoning to current literature.