Abstract:Paraneoplastic cerebellar degeneration is rare and noteworthy in children. In this
7-year-old, it was documented to have occurred within a year of ataxia presentation. The
instigating cancer was stage III adrenal adenocarcinoma, remitted after surgical resection
at age 2. When her severe ataxia progressed, neuroinflammation was characterized by high
cerebrospinal fluid Purkinje cell cytoplasmic antibody type 1 titers, oligoclonal bands,
and neurofilament light chain. The immunotherapy strategy was to replace I… Show more
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