Intensity-modulated radiation therapy (IMRT) for meningioma

Uy, N.W.; Woo, Shiao Y.; Teh, Bin S.; Yuan, Wei; Carpenter, L. Steven; Chiu, J. Kam; Lu, Haiquan; Gildenberg, Phillip; Trask, Todd; Grant, Walter H.; Butler, E. Brian

doi:10.1016/s0360-3016(02)02823-7

Cited by 109 publications

(54 citation statements)

References 25 publications

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“…Encouraging data with stereotactic external beam radiotherapy and IMRT, however, have also been reported (Uy et al, 2002;Zabel et al, 2005) and comparative studies need to be conducted to assess whether there is any demonstrable difference in tumour control or complications between these techniques and proton radiotherapy.…”

Section: Benign Meningiomamentioning

confidence: 99%

Proton beam therapy

et al. 2005

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Conventional radiation therapy directs photons (X-rays) and electrons at tumours with the intent of eradicating the neoplastic tissue while preserving adjacent normal tissue. Radiation-induced damage to healthy tissue and second malignancies are always a concern, however, when administering radiation. Proton beam radiotherapy, one form of charged particle therapy, allows for excellent dose distributions, with the added benefit of no exit dose. These characteristics make this form of radiotherapy an excellent choice for the treatment of tumours located next to critical structures such as the spinal cord, eyes, and brain, as well as for paediatric malignancies.

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Section: Benign Meningiomamentioning

confidence: 99%

Proton beam therapy

et al. 2005

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“…The safety and efficacy of IMRT in benign/low-grade meningiomas has now been firmly established by several prospective clinical outcome studies (Table 4) [23][24][25][26][27][28]. Most series report excellent disease outcomes at 3-5 years with Kaplan-Meier estimates of local control and/or PFS well over 90% and acceptable significant late toxicity (around 5%).…”

Section: Discussionmentioning

confidence: 97%

Helical Tomotherapy Based Image-Guided Intensity-Modulated Radiation Therapy for Complex, Irregular, Residual, Recurrent, Progressive Benign/ Low-Grade Meningiomas

Gupta¹,

Wadasadawala²,

Phurailatpam³

2012

J Nucl Med Radiat Ther

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“…14,105 The ability of IMRT to achieve excellent dose distribution for the most complex targets allows moderate dose escalation to the tumour while respecting dose constraints. [106][107][108] Proton radiotherapy results in an even better capability to cover the target while sparing surrounding critical structures, especially in the case of tumours with challenging "L" and "C" shapes, compared to photon IMRT and SRT.…”

Section: Discussionmentioning

confidence: 99%

Review of photon and proton radiotherapy for skull base tumours

Fossati

Vavassori²,

Deantonio

et al. 2016

Reports of Practical Oncology & Radiotherapy

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a b s t r a c tAn extremely large variety of benign and malignant tumours occur at skull base; these tumour lesions are in the proximity to structures deputed to relevant physiologic functions, limiting extensive surgical approaches to this body district. Most recent progresses of surgery and radiotherapy have allowed to improve local control with acceptable rates of side effects. Various photon radiotherapy techniques are employed, including 3-dimensional conformal radiotherapy, intensity modulated radiotherapy (IMRT), stereotactic radiotherapy (SRT) and brachytherapy that is manly limited to the treatment of primary or recurrent nasopharyngeal carcinoma. Proton beam radiotherapy is also extensively used thanks to its physical characteristics. Our review, focusing in particular on meningioma, chordoma, and chondrosarcoma, suggests that proton therapy plays a major role in the treatment of malignant tumours whereas photon therapy still plays a relevant role in the treatment of benign tumour lesions.

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Intensity-modulated radiation therapy (IMRT) for meningioma

Cited by 109 publications

References 25 publications

Proton beam therapy

Proton beam therapy

Helical Tomotherapy Based Image-Guided Intensity-Modulated Radiation Therapy for Complex, Irregular, Residual, Recurrent, Progressive Benign/ Low-Grade Meningiomas

Review of photon and proton radiotherapy for skull base tumours

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