Intensifying Radiation Treatment in Advanced/Poor Prognosis Laryngeal, Hypopharyngeal (LH), and Oropharyngeal Cancers (OPC) Using PET–CT Based Dose Escalation Strategies—INTELHOPE (Clin Trial.gov NCT02757222)

Abstract

Conclusion: CAS incidence is high after head and neck radiotherapy, gradually rising over time. No clear dose-response effect between carotid dose and CAS was identified. Carotid artery screening and preventative strategies should be employed in this patient population.