Intense pulsed light treatment for inflammatory skin diseases: a review

Cai, Yujia; Zhu, Yuan; Wang, Yanqing; Xiang, Wenzhong

doi:10.1007/s10103-022-03620-1

Cited by 17 publications

(12 citation statements)

References 51 publications

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“…The newer versions permit quartz or sapphire crystals to filter the wavelength spectrum in the direction of longer wavelengths, which affect deeper skin structures relative to the epidermis [33]. The detachable filters also allow the selection of the wavelength required for certain lesions [34,35]. In a similar fashion, the pulse energy has been fractionated, and novel cooling mechanisms have been developed to prevent skin harm [34,35].…”

Section: Discussionmentioning

confidence: 99%

“…The detachable filters also allow the selection of the wavelength required for certain lesions [34,35]. In a similar fashion, the pulse energy has been fractionated, and novel cooling mechanisms have been developed to prevent skin harm [34,35]. Among the possible adverse effects, discomfort during administration is the most common.…”

Section: Discussionmentioning

confidence: 99%

“…Pigmentation alterations and hypertrophic scars are seldom seen. Ocular problems have also been reported when using high fluences such as 20 J/ cm 2 [34]. There have been reports of anterior uveitis, iris transillumination abnormalities, and modifications that result in eye synechiae and pupillary obstruction followed by angle closure [36][37][38][39].…”

Section: Discussionmentioning

confidence: 99%

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Managing Severe Evaporative Dry Eye with Intense Pulsed Light Therapy

Qin

Chen

et al. 2023

Ophthalmol Ther

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Introduction: This study assessed the efficacy and safety of intense pulsed light (IPL) therapy in participants with severe evaporative dry eye disease (DED). Methods: This randomized, controlled, singlecenter study included 49 adult participants (C 18 years) with severe evaporative DED who received either IPL therapy (n = 56 eyes) or sham therapy (n = 42 eyes) three times. The primary efficacy parameters were ocular surface disease index (OSDI) score, non-invasive tear breakup time (NITBUT), tear film lipid layer (TFLL), conjunctivocorneal staining score (CS), MG Score, meibomian gland (MG) quality, and MG expression score. Results: The mean ages for the IPL group and the control group were 28.05 ± 3.41 years (57.1% female) and 28.14 ± 3.53 years (52.4% female), respectively. Comparison between the IPL group and the control group found significant differences in the mean OSDI score (22.16 ± 6.08 vs. 42.38 ± 6.60; P \ 00.01), NITBUT (6.27 ± 0.84 vs.3.86 ± 0.68; P \ 0.001), TFLL (2.14 ± 0.44 vs. 3.45 ± 0.50; P \ 0.001), MG Score (1.34 ± 0.55 vs. 1.88 ± 0.33; P \ 0.001), MG quality (1.59 ± 0.07 vs. 2.67 ± 0.08), and MG expression (1.54 ± 0.57 vs. 2.45 ± 0.55) at 12 weeks follow-up; however, there was no significant difference in CS (3.32 ± 1.11 vs. 3.74 ± 1.04; P = 0.063). Conclusion:The findings suggest that IPL therapy is clinically beneficial in ameliorating the signs and symptoms of severe evaporative dry eye disease.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Managing Severe Evaporative Dry Eye with Intense Pulsed Light Therapy

Qin

Chen

et al. 2023

Ophthalmol Ther

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“…One limitation of this study was the assessment of patients' quality of life before and after treatment. Nonetheless, it has been reported in the literature in a study wherein patients were randomized for the treatment to one axillar, groin, or inframammary area with laser therapy while the contralateral side received no treatment and served as control 16,30 . Implementing a survey would add validity to laser therapy as a potential treatment for HS to improve patients' lives.…”

Section: Discussionmentioning

confidence: 99%

A Retrospective Review of Laser Therapy for Treatment of Hidradenitis Suppurativa

Fortoul,

Macias Martinez,

Ventura Rodriguez

et al. 2023

Ann Plast Surg

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Purpose Hidradenitis suppurativa (HS) is a chronic inflammatory disease characterized by painful and foul-smelling cystic nodules and sinus tracts in the apocrine gland-bearing regions. The treatment options include topical, intralesional, systemic, and surgical modalities. Currently, the most novel therapy is laser therapy to provide localized treatment without systemic adverse effects. However, data regarding patient outcomes after laser treatment are limited because of the low prevalence of this disease. This study aimed to evaluate the efficacy of laser therapy as a treatment modality for patients with HS. Methods A retrospective review cohort analysis of patients with HS undergoing laser treatment between 2016 and 2021 was conducted. Patient demographics, lesion location(s), Hurley stage, age of onset and diagnosis, treatment length, type, outcomes, and complications were analyzed. Results Ninety-four patients met the inclusion criteria; on average, patients were treated with 5.8 laser sessions for 14.8 months with no complications and minor blood loss. Hidradenitis suppurativa progression commonly starts during puberty, with a median onset of 13.8 years and diagnosis of HS at 16.2 years. All patients (n = 94) showed an improvement in HS disease severity: 59.6% completed treatment, 12.0% are currently undergoing treatment, and 26.0% were lost to follow-up. Conclusions Laser therapy is an effective and safe therapy for HS leading to improved quality of life and should be considered in the treatment and management of HS.

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“…So far, IPL has been used extensively to treat a variety of pigmentation diseases. 21 It converts light energy into heat energy, directly targeting melanin in the epidermis and making melanosomes in epidermis move to the upper layer of skin quickly, showing the characteristics of decolorization. 22 There are few literature reports confirming the effectiveness of IPL for treating Riehl’s melanosis.…”

Section: Laser Therapymentioning

confidence: 99%

Research Advances in the Treatment of Riehl’s Melanosis

Xu¹,

Huang²,

Wu³

et al. 2023

CCID

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Riehl’s melanosis (RM) is a contact photodermatitis, with fast progressive gray-brown skin pigmentation as the main manifestation, which can seriously affect the psychology and physiology of patients. Currently, although the etiological factors of Riehl’s melanosis is still be unknown, the existing literature proves clearly the cause of it is related to the contacting with suspected allergens. For decades, there has been no standard method for the treatment of RM, but with both conventional drug therapy and laser therapy having been attempted. Topical application of bleaching agents is mainly used as an auxiliary treatment modality. The laser treatment modality remains a hot spot, among which Q-switched Nd:YAG laser is well received for RM. Positive outcomes have been achieved by the combined treatment modalities attempted in recent years also achieve positive outcomes. The purpose of this paper is to review and summarize recent advances in the treatment of the disease.

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Intense pulsed light treatment for inflammatory skin diseases: a review

Cited by 17 publications

References 51 publications

Managing Severe Evaporative Dry Eye with Intense Pulsed Light Therapy

Managing Severe Evaporative Dry Eye with Intense Pulsed Light Therapy

A Retrospective Review of Laser Therapy for Treatment of Hidradenitis Suppurativa

Research Advances in the Treatment of Riehl’s Melanosis

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