Intense Focused Ultrasound Tightening in Asian Skin: Clinical and Pathologic Results

Suh, Dong Hye; Shin, Min Kyung; Lee, Sang Jun; Rho, Ji Ho; Lee, Mu Hyoung; Kim, Nack In; Song, Kye Yong

doi:10.1111/j.1524-4725.2011.02094.x

Cited by 116 publications

(103 citation statements)

References 19 publications

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“…In addition to traditional rejuvenating surgeries, such as facelifts and blepharoplasty, non-invasive procedures aimed at remodelling the skin surface and targeting the deep soft tissues, including the facial fat and muscles, are becoming popular. [14][15][16][17] Maintaining control of facial volume and conditioning of the facial soft tissues are important targets for non-invasive rejuvenating strategies.…”

Section: Introductionmentioning

confidence: 99%

MR relaxometry for the facial ageing assessment: the preliminary study of the age dependency in the MR relaxometry parameters within the facial soft tissue

Watanabe

Buch

Fujita

et al. 2015

Dentomaxillofacial Radiology

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Objectives: To investigate the location-specific tissue properties and age-related changes of the facial fat and facial muscles using quantitative MRI (qMRI) analysis of longitudinal magnetization (T1) and transverse magnetization (T2) values. Methods: 38 subjects (20 males and 18 females, 0.5-87 years old) were imaged with a mixed turbo-spin echo sequence at 1.5 T. T1 and T2 measurements were obtained within regions of interest in six facial fat regions including the buccal fat and subcutaneous cheek fat, four eyelid fat regions (lateral upper, medial upper, lateral lower and medial lower) and five facial muscles including the orbicularis oculi, orbicularis oris, buccinator, zygomaticus major and masseter muscles bilaterally. Results: Within the zygomaticus major muscle, age-associated T1 decreases in females and T1 increases in males were observed in later life with an increase in T2 values with age. The orbicularis oculi muscles showed lower T1 and higher T2 values compared to the masseter, orbicularis oris and buccinator muscles, which demonstrated small age-related changes. The dramatic age-related changes were also observed in the eyelid fat regions, particularly within the lower eyelid fat; negative correlations with age in T1 values (p , 0.0001 for age) and prominent positive correlation in T2 values in male subjects (p , 0.0001 for male 3 age). Age-related changes were not observed in T2 values within the subcutaneous cheek fat. Conclusions: This study demonstrates proof of concept using T1 and T2 values to assess agerelated changes of the facial soft tissues, demonstrating tissue-specific qMRI measurements and non-uniform ageing patterns within different regions of facial soft tissues. Dentomaxillofacial Radiology (2015) 44, 20150047. doi: 10.1259/dmfr.20150047 Cite this article as: Watanabe M, Buch K, Fujita A, Christiansen CL, Jara H, Sakai O. MR relaxometry for the facial ageing assessment: the preliminary study of the age dependency in the MR relaxometry parameters within the facial soft tissue. Dentomaxillofac Radiol 2015; 44: 20150047.Keywords: ageing; facial muscles; adipose tissue; magnetic resonance imaging; quantitative evaluation IntroductionThe face is a complex, multifunctional structure responsible for conveying various emotional expressions. The investigations into the mechanisms of facial ageing have revealed a multifactorial process involving a combination of structures with functional and structural changes including loss of elasticity, facial fat atrophy, weakened muscular support and bony Correspondence to: Dr Memi Watanabe. E-mail: memi.watanabe@bmc.org Cindy L Christiansen received funds from Department of Radiology, Boston University School of Medicine, for statistical support. Hernán Jara is named inventor in several patents held by Boston University and Boston Medical Center pertaining to quantitative MRI and Synthetic MRI algorithms and these could be licensed to a major MRI manufacturer (negotiations are taking place with GE Healthcare). Hernán Jara also has received royal...

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Section: Introductionmentioning

confidence: 99%

MR relaxometry for the facial ageing assessment: the preliminary study of the age dependency in the MR relaxometry parameters within the facial soft tissue

Watanabe

Buch

Fujita

et al. 2015

Dentomaxillofacial Radiology

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“…28 MFU-V uses intense focused ultrasound for precise microcoagulation of subcutaneous tissues 29,30 leading to an initial contraction and denaturation of collagen fibers; subsequent stimulation of de novo collagen synthesis and normalization of elastin fibers results in skin tightening. 31,32 To date, limited data are available concerning the combined use of MFU-V with other aesthetic treatments. One retrospective study assessed the combined use of MFU-V and ablative fractionated laser resurfacing to improve skin laxity and rhytides on the face and neck.…”

Section: Discussionmentioning

confidence: 99%

Combining Microfocused Ultrasound With Botulinum Toxin and Temporary and Semi-Permanent Dermal Fillers

Fabi

Goldman

Mills

et al. 2016

Dermatologic Surgery

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“…Microfocused Ultrasound (MU) is a noninvasive technology used for correction of moderate tissue laxity [7][8][9]. By delivering short duration pulses of transcutaneous ultrasound energy, a thermal coagulative damage is produced called thermal injury zone (TIZ) from deep dermis to the superficial musculaponeurotic system (SMAS) [7,8,10].…”

Section: Discussionmentioning

confidence: 99%

Combination of Treatments in Nonsurgical Facelift Performance to Conduce a Case of Severe Photoaging

Salomao¹,

Gasques²,

Nascimento³

et al. 2016

Arch Med

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Intense Focused Ultrasound Tightening in Asian Skin: Clinical and Pathologic Results

Abstract: IFUS is a safe, effective, noninvasive procedure to tighten the facial skin of Asian patients. Improvement is associated with greater production of dermal collagen and straightening of dermal elastic fibers.

Cited by 116 publications

References 19 publications

MR relaxometry for the facial ageing assessment: the preliminary study of the age dependency in the MR relaxometry parameters within the facial soft tissue

MR relaxometry for the facial ageing assessment: the preliminary study of the age dependency in the MR relaxometry parameters within the facial soft tissue

Combining Microfocused Ultrasound With Botulinum Toxin and Temporary and Semi-Permanent Dermal Fillers

Combination of Treatments in Nonsurgical Facelift Performance to Conduce a Case of Severe Photoaging

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