In the modern era, due to several confliction or uncertainty in the aircraft, Electromagnetic Interference (EMI) or Radio Frequency Interference (RFI) issues occurred, frequently. The main reason behind it several disturbances generated by an external source which imitate wireless circuits with the help of conduction, electrostatic coupling, and electromagnetic induction. These disturbances may decrease the performance of the circuits or sometimes fully stop the operations. Main challenges in EMI are modeling and simulation for modern and future wireless communication systems and networks taking into account nonlinear interference effects. In this paper, overviews of several issues of EMI or RFI are illustrated.