Integrin-Dependent Regulation of Small GTPases: Role in Cell Migration

Pawar, Archana; Balasubramanian, Nagaraj

doi:10.1007/s41745-016-0010-4

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Cellular Targets For Magnetogenetics1

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2022

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“…77,78 This cytoskeleton dynamics activates cell remodelling and downstream signalling, being the small Rho GTPases vital mediators of this pathway. 79 Several studies of proliferation and osteogenic differentiation of stem cells have employed integrins as targets for magnetic actuators functionalized with RGD (See section 4). 14,[80][81][82] The RGD peptide is present within extracellular matrix proteins such as fibronectin, fibrinogen or osteopontin among others, and represents their principal binding domain to integrins.…”

Section: Cellular Targets For Magnetogeneticsmentioning

confidence: 99%