Integrative network pharmacology and transcriptomics analysis reveal the mechanism of Tanreqing in the treatment of acne vulgaris

Ren, Xing; Zhou, Na; Li, Dongying; Yang, Jing; Wang, Yunong; He, Gaiying; Ma, Shuhua; Sun, Yanan; Wang, Yi

doi:10.1016/j.phyplu.2023.100505

Cited by 1 publication

(1 citation statement)

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“…Acne vulgaris is a skin problem that can significantly affect the life of the individual who experiences it. This is mainly due to its general location on the face, which is difficult to hide and often causes social discomfort (Ren et al, 2023). In addition, long-term impacts such as postinflammatory hyperpigmentation and scars that may remain for years, even throughout life, can also significantly affect the quality of life of people who experience them (Safitri et al, 2020) The etiology of this disease still needs to be identified.…”

Section: Introductionmentioning

confidence: 99%

The Relationship Between the Severity of Acne Vulgaris and the Quality of Life of Prima Indonesia University Medical Faculty Students

Natali,

Ayu Athifa Serena,

Sari Mutia

2023

ijsh

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Acne vulgaris, or acne, is a chronic inflammatory disease of the pilosebaceous follicles, characterized by the appearance of open and closed comedones, papules, pustules, nodules, seborrhea, and cysts. Acne vulgaris can occur in teenagers and young adults, such as medical school students, affecting their quality of life. This research aimed to determine the relationship between the severity of acne vulgaris and the quality of life of students. This type of research is analytical observational research with a cross-sectional design. The population in this study were students from the Faculty of Medicine, Prima Indonesia University, class 2020 – 2021, who suffered from acne vulgaris. The research sample obtained was 38 people. Sampling was purposive sampling. Data was obtained from a questionnaire filled out via the Google Form link. Data were analyzed univariately and bivariately using the Spearman Rho Rank test at a % confidence level of 95% (a=0.05). The results showed that the severity of acne vulgaris of students at the Faculty of Medicine, Prima Indonesia University (71.1%) was mild. The quality of life of students was in the mild disorder category (52.6%). The severity of acne vulgaris in students is significantly related to the quality of life of students at the Faculty of Medicine, Prima Indonesia University (p = 0.001 < 0.05), with the close relationship (correlation coefficient) of the two variables in the medium category (r = 0.522). The majority of respondents indicated the presence of mild acne vulgaris, reflecting the potential for awareness of good skin health practices.

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Section: Introductionmentioning

confidence: 99%