Integrative analyses of bulk, single-cell and spatial transcriptomics identified diabetes mellitus-related signature as a prognostic factor in pancreatic adenocarcinoma
Le Tang,
Tongji Xie,
Guangyu Fan
et al.
Abstract:Purpose
Pancreatic adenocarcinoma (PAAD) is a deadly disease, particularly for those with diabetes mellitus (DM). While there have been various studies on prognostic factors in pancreatic cancer, few have specifically focused on PAAD patients with DM. This study aimed to identify differentially expressed genes (DEGs) between DM and non-DM individuals and develop a predictive model.
Materials and Methods
PAAD patients with DM were divided into training (70%) and test (30%) groups, and OS-associated genes were… Show more
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