Integration of orientation information in amblyopia

Mansouri, Behzad; Allen, Harriet A.; Hess, Robert F.; Dakin, Steven C.; Ehrt, Oliver

doi:10.1016/j.visres.2004.06.017

Cited by 28 publications

(36 citation statements)

References 61 publications

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“…The correlation of the domain "distance estimation" to both acuity and degree of binocular vision may suggest that both are limiting factors in final reaching to and grasping of objects (prehension) [9]. The domain "visual disorientation" may be functionally analogous to positional uncertainty [10] and thus possibly be influenced by the acuity of the amblyopic eye. There is, to our knowledge, no prior research that might explain the correlation of the domain "social contact and cosmetic problems" with latent nystagmus.…”

Section: Discussionmentioning

confidence: 99%

Amblyopia and Strabismus Questionnaire (A&SQ): clinical validation in a historic cohort

Graaf

Sterre

Saar

et al. 2007

Graefes Arch Clin Exp Ophthalmol

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Background We recently developed the Amblyopia & Strabismus Questionnaire (A&SQ) to assess the quality of life in amblyopia and/or strabismus patients, and evaluated its content and criterion validity. The A&SQ was now validated clinically by correlating its outcome with past and current orthoptic parameters in a historic cohort of amblyopia and/or strabismus patients. Methods The cohort was derived from all 471 patients who were treated by occlusion therapy in the Waterland Hospital in Purmerend between 1968Purmerend between and 1974Purmerend between and born between 1962Purmerend between and 1972. All children with insufficient visual acuity from the Waterland area had been referred to a single ophthalmologist and orthoptist. Of these, 203 were traced, and 174 filled out the A&SQ. In 137 of these, binocular vision, visual acuity, and angle of strabismus were reassessed 30-35 years after occlusion therapy. These clinical parameters were correlated with the five A&SQ

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Section: Discussionmentioning

confidence: 99%

Amblyopia and Strabismus Questionnaire (A&SQ): clinical validation in a historic cohort

Graaf

Sterre

Saar

et al. 2007

Graefes Arch Clin Exp Ophthalmol

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“…This dependency of performance in amblyopia on the number of elements has been previously reported for a mean orientation discrimination task with Gabor patches. 42 However, even with a reduced number of dipole elements, three strabismic amblyopes could still not reliably detect the Glass pattern structure.…”

Section: Global Form Discrimination In Amblyopiamentioning

confidence: 99%

Concurrent Investigation of Global Motion and Form Processing in Amblyopia: An Equivalent Noise Approach

Joshi

Simmers

Jeon

2016

Invest. Ophthalmol. Vis. Sci.

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PURPOSE. Directly comparing the motion and form processing in neurologic disorders has remained difficult due to the limitations in the experimental stimulus. In the current study, motion and form processing in amblyopia was characterized using random dot stimuli in different noise levels to parse out the effect of local and global processing on motion and form perception. METHODS.A total of 17 amblyopes (8 anisometropic and 9 strabismic), and 12 visually normal subjects monocularly estimated the global direction of motion and global orientation in random dot kinematograms (RDK) and Glass patterns (Glass), whose directions/orientations were drawn from normal distributions with a range of means and variances that served as external noise. Direction/orientation discrimination thresholds were measured without noise first then variance threshold was measured at the multiples of the direction/orientation threshold. The direction/orientation and variance thresholds were modelled to estimate internal noise and sampling efficiency parameters.RESULTS. Overall, the thresholds for Glass were higher than RDK for all subjects. The thresholds for both Glass and RDK were higher in the strabismic eyes compared with the fellow and normal eyes. On the other hand, the thresholds for anisometropic amblyopic eyes were similar to the normal eyes. The worse performance of strabismic amblyopes was best explained by relatively low sampling efficiency compared with other groups (P < 0.05). CONCLUSIONS.A deficit in global motion and form perception was only evident in strabismic amblyopia. Contrary to the dorsal stream deficiency hypothesis assumed in other developmental disorders, deficits were present in both motion (dorsal) and form (ventral) processing.

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“…This distinction is highlighted in our previous studies of the clinical condition, amblyopia. Amblyopes can perform normally in either a form (Mansouri et al, 2004;Mansouri et al, 2005) or motion ) equivalent noise task, but exhibit anomalies in either form (Simmers et al, 2005) or motion AaenStockdale et al, 2007;Simmers et al, 2003;Simmers et al, 2006) coherence tasks. Thus, we believe that fundamentally different operations underlie equivalent noise and coherence tasks; the former involving purely integrative processes and the latter an additional segregative process.…”

Section: Comparison With Equivalent Noise Paradigmsmentioning

confidence: 99%

Orientation coherence sensitivity

2012

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We developed a global orientation coherence task for the assessment of global form processing along similar lines to the global motion coherence task. The task involved judgments of global orientation for an array of limited duration 1-D Gabors, some of which were signal (signal orientation) and some of which were noise (random orientation). We address two issues. First: Do motion and form global processing have similar dependencies? And second: Can global sensitivity be explained solely in terms of integrative function? While most dependencies (e.g., contrast, spatial scale, and field size) are similar for form and motion processing, there is a greater dependence on eccentricity for form processing. Sensitivity for global tasks involves more than just integration by filters broadly tuned for orientation. Results are best modeled by filters with narrowband orientation tuning that effectively segregate as well as integrate global information.

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Integration of orientation information in amblyopia

Cited by 28 publications

References 61 publications

Amblyopia and Strabismus Questionnaire (A&SQ): clinical validation in a historic cohort

Amblyopia and Strabismus Questionnaire (A&SQ): clinical validation in a historic cohort

Concurrent Investigation of Global Motion and Form Processing in Amblyopia: An Equivalent Noise Approach

Orientation coherence sensitivity

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