“…Due to its widespread use and high fidelity, the integration of MRI findings, as a functional biomarker of risk, is critical in the current and future generations of risk calculators used for prostate cancer detection [4]. Hence, risk calculators integrating MRI findings when available, can truly derive recommendations based on readily available, pre-biopsy datapoints to help guide shared decision-making in the prebiopsy setting, with the ultimate goals of minimizing the number and frequency of biopsies, without compromising the diagnosis of clinically-significant prostate cancers that would benefit from early diagnosis and curative treatment [5,6].…”