Integration of hyperspectral imaging and transcriptomics from individual cells with HyperSeq
Yike Xie,
Abbas Habibalahi,
Ayad G. Anwer
et al.
Abstract:Microscopy and omics are complementary approaches to probe the molecular state of cells in health and disease, combining granularity with scalability. While important advances have been achieved over the last decade in each area, integrating both imaging- and sequencing-based assays on the same cell has proven challenging. In this study, a new approach called HyperSeq that combines hyperspectral autofluorescence imaging with transcriptomics on the same cell is demonstrated. HyperSeq was applied to Michigan Can… Show more
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