Integration of high‐resolution mass spectrometry technology with molecular network analysis and systems biology techniques to elucidate the active ingredients and mechanisms of Shiduqing capsules
Zhiyan Liu,
Shuang Li,
Lei Wang
et al.
Abstract:RationaleShiduqing Capsules, a well‐known Chinese patent medicine, are widely used clinically for the treatment of pruritus. However, to date, there is a lack of research on its pharmacological substances and mechanisms of action.MethodsIn the current study, the chemical components of Shiduqing Capsules were identified using UHPLC‐QE‐Orbitrap‐MS technology. Molecular network analysis was employed to identify structurally similar compounds to the known chemical components. The potential molecular targets of the… Show more
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