Integration of Fractal Biosensor in a Digital Microfluidic Platform

Mashraei, Yousof; Sivashankar, Shilpa; Büttner, U.; Salama, Khaled N.

doi:10.1109/jsen.2016.2578440

Cited by 18 publications

(8 citation statements)

References 49 publications

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“…[3] In contrast, μ-SCs are promising for such applications because of their charge-discharge (CD) rate, high power density, and long cycle life. [20,21] Given the potential advantages of fractal designs, many research groups have recently started to work on fractal electrode designs for several applications, such as in characterization of complex irregular surfaces, [22] neural stimulation, [23] high-density CMOS capacitors, [24] optoelectronic devices, [25,26] biosensors, [27] stretchable electronics, [28] and in radio frequency (RF) MEMS capacitors. [20,21] Given the potential advantages of fractal designs, many research groups have recently started to work on fractal electrode designs for several applications, such as in characterization of complex irregular surfaces, [22] neural stimulation, [23] high-density CMOS capacitors, [24] optoelectronic devices, [25,26] biosensors, [27] stretchable electronics, [28] and in radio frequency (RF) MEMS capacitors.…”

Section: Introductionmentioning

confidence: 99%

“…[4] In addition, compared to thin-film batteries, μ-SCs charge most efficiently by drawing the maximum current that the source can supply, irrespective of voltage, thereby making supercapacitors more appropriate www.advelectronicmat.de structure. [20,21] Given the potential advantages of fractal designs, many research groups have recently started to work on fractal electrode designs for several applications, such as in characterization of complex irregular surfaces, [22] neural stimulation, [23] high-density CMOS capacitors, [24] optoelectronic devices, [25,26] biosensors, [27] stretchable electronics, [28] and in radio frequency (RF) MEMS capacitors. [21,29] Fractal designs have also been theoretically predicted to enhance the performance of electrochemi cal systems since they maximize the electrochemically active surface area while minimizing energy lost during the transport of ions within the fractal network.…”

Section: Introductionmentioning

confidence: 99%

“…A fractal design is generally prepared using an algorithm with a finite number of iterations by starting from an initial structure or unit‐cell design (called a “generator”) that is replicated many times at different scales, positions, and directions to cultivate the final fractal structure . Given the potential advantages of fractal designs, many research groups have recently started to work on fractal electrode designs for several applications, such as in characterization of complex irregular surfaces, neural stimulation, high‐density CMOS capacitors, optoelectronic devices, biosensors, stretchable electronics, and in radio frequency (RF) MEMS capacitors . Fractal designs have also been theoretically predicted to enhance the performance of electrochemical systems since they maximize the electrochemically active surface area while minimizing energy lost during the transport of ions within the fractal network .…”

Section: Introductionmentioning

confidence: 99%

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Fractal Electrochemical Microsupercapacitors

Hota

Jiang

Mashraei

et al. 2017

Adv Elect Materials

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The first successful fabrication of microsupercapacitors (μ‐SCs) using fractal electrode designs is reported. Using sputtered anhydrous RuO2 thin‐film electrodes as prototypes, μ‐SCs are fabricated using Hilbert, Peano, and Moore fractal designs, and their performance is compared to conventional interdigital electrode structures. Microsupercapacitor performance, including energy density, areal and volumetric capacitances, changes with fractal electrode geometry. Specifically, the μ‐SCs based on the Moore design show a 32% enhancement in energy density compared to conventional interdigital structures, when compared at the same power density and using the same thin‐film RuO2 electrodes. The energy density of the Moore design is 23.2 mWh cm−3 at a volumetric power density of 769 mW cm−3. In contrast, the interdigital design shows an energy density of only 17.5 mWh cm−3 at the same power density. We show that active electrode surface area cannot alone explain the increase in capacitance and energy density. We propose that the increase in electrical lines of force, due to edging effects in the fractal electrodes, also contribute to the higher capacitance. This study shows that electrode fractal design is a viable strategy for improving the performance of integrated μ‐SCs that use thin‐film electrodes at no extra processing or fabrication cost.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Fractal Electrochemical Microsupercapacitors

Hota

Jiang

Mashraei

et al. 2017

Adv Elect Materials

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“…In addition, the ability to miniaturize and lower the cost of IDE sensors offers the potential to operate with a low volume of samples and promotes their plausible integration with electronics in a reasonably simpler way. Particularly, IDEs offer a prospect for accessing the requisite low-power sensing platforms, such as lab-on-open chip applications. − …”

mentioning

confidence: 99%

MOFs for the Sensitive Detection of Ammonia: Deployment of fcu-MOF Thin Films as Effective Chemical Capacitive Sensors

et al. 2017

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This work reports on the fabrication and deployment of a select metal-organic framework (MOF) thin film as an advanced chemical capacitive sensor for the sensing/detection of ammonia (NH) at room temperature. Namely, the MOF thin film sensing layer consists of a rare-earth (RE) MOF (RE-fcu-MOF) deposited on a capacitive interdigitated electrode (IDE). Purposely, the chemically stable naphthalene-based RE-fcu-MOF (NDC-Y-fcu-MOF) was elected and prepared/arranged as a thin film on a prefunctionalized capacitive IDE via the solvothermal growth method. Unlike earlier realizations, the fabricated MOF-based sensor showed a notable detection sensitivity for NH at concentrations down to 1 ppm, with a detection limit appraised to be around 100 ppb (at room temperature) even in the presence of humidity and/or CO. Distinctly, the NDC-Y-fcu-MOF based sensor exhibited the required stability to NH, in contrast to other reported MOFs, and a remarkable detection selectivity toward NH vs CH, NO, H, and CH. The NDC-Y-fcu-MOF based sensor exhibited excellent performance for sensing ammonia for simulated breathing system in the presence of the mixture of carbon dioxide and/or humidity (water vapor), with no major alteration in the detection signal.

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“…Further, the detection of protein functionalized on the streptavidin molecules by the biotin labelled beads were carried out by the EWOD actuation [110]. In addition, instead of traditional electrodes, specifically designed fractal capacitive electrodes were used as actuation electrodes and also as the sensing electrode for the EWOD system for the rapid immunodetection of C-reactive proteins [111].…”

Section: Detection Of Biological Analytesmentioning

confidence: 99%

Electrowetting-on-dielectric (EWOD): Current perspectives and applications in ensuring food safety

Barman¹,

Khan²,

Chatterjee³

et al. 2020

Journal of Food and Drug Analysis

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Digital microfluidic (DMF) platforms have contributed immensely to the development of multifunctional lab-on-chip systems for performing complete sets of biological and analytical assays. Electrowetting-on-dielectric (EWOD) technology, due to its outstanding flexibility and integrability, has emerged as a promising candidate for such lab-on-chip applications. Triggered by an electrical stimulus, EWOD devices allow precise manipulation of single droplets along the designed electrode arrays without employing external pumps and valves, thereby enhancing the miniaturization and portability of the system towards transcending important laboratory assays in resource-limited settings. In recent years, the simple fabrication process and reprogrammable architecture of EWOD chips have led to their widespread applications in food safety analysis. Various EWOD devices have been developed for the quantitative monitoring of analytes such as food-borne pathogens, heavy metal ions, vitamins, and antioxidants, which are significant in food samples. In this paper, we reviewed the advances and developments in the design of EWOD systems for performing versatile functions starting from sample preparation to sample detection, enabling rapid and high-throughput food analysis.

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Integration of Fractal Biosensor in a Digital Microfluidic Platform

Cited by 18 publications

References 49 publications

Fractal Electrochemical Microsupercapacitors

Fractal Electrochemical Microsupercapacitors

MOFs for the Sensitive Detection of Ammonia: Deployment of fcu-MOF Thin Films as Effective Chemical Capacitive Sensors

Electrowetting-on-dielectric (EWOD): Current perspectives and applications in ensuring food safety

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