Integration of Bioinformatics Tools for Proteomics Research

Abstract

Proteomics is the large-scale study of proteins, particularly their structures and functions. Proteins are vital parts of living organisms, as they are the main components of the physiological metabolic pathways of cells. Proteomics has shown a great achievement since a decade or long. It has rather a more complicated system than genomics. The complexity arrived when proteome differed from cell to cell and from time to time.Since a decade or two MS has been proved to be an outstanding technology for the analysis of complex mixtures along with 2-D gel electrophoresis. This technology is being applied in fields like clinical sciences, medical sciences, environmental, life sciences, engineering etc. Various approaches are being discovered day by day which are highlighted. A proteomic-based approach was applied to characterize cellular responses of neuronal cells to Pyridostigmine Bromide