Integration of 2-deoxy-2-[18F] fluoro-d-glucose PET/CT into clinical management of patients with Wegener’s granulomatosis

Özmen, Özlem; Tatci, Ebru; Köksal, Deniz; Dadali, Yeliz; Özaydin, Esra; Arslan, Nuri

doi:10.1007/s12149-013-0769-6

Cited by 17 publications

(6 citation statements)

References 15 publications

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“…Besides, it is valuable in terms of showing unexpected involvement of the body. Ozmen et al showed that FDG PET/CT determined in 46% of patient population unexpected involvement areas such as great vessels, ear, spleen, kidney, duodenum, trachea and skin which were difficult to detect by conventional imaging procedures [31]. In our study, expect upper and lower respiratory tract and kidney, FDG PET/CT detected palata and prostate involvement.…”

Section: Discussionsupporting

confidence: 54%

Granülamatosis Polianjitis tanılı beş olgunun Pozitron Emisyon Tomografisi ile değerlendirilmesi

Ogan¹,

Demirci²,

Demirbağ³

et al. 2017

TURKISH JOURNAL of CLINICS and LABORATORY

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Granulomatosis with polyangiitis (GPA) formerly Wegener's Granulomatosis, is characterized by granulomatosis necrotizing vasculitis that primarily involves upper respiratory tracts, lung and kidney. There are two types of disease, 'limited' and 'generalized'. Radiological findings are seen as multiple bilateral nodules that change from a few millimeters to centimeters in size or parenchymal infiltrations, cavitations or nodules presented with cavitations. These nodules sometimes can be confused with malignancy in terms of the size and appearance. In this study, we discussed the role of positron emission tomography/ computerized tomography (PET/CT) in the initial evaluation of patients with the diagnosis of GPA mimicking malignancy.

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Section: Discussionsupporting

confidence: 54%

Granülamatosis Polianjitis tanılı beş olgunun Pozitron Emisyon Tomografisi ile değerlendirilmesi

Ogan¹,

Demirci²,

Demirbağ³

et al. 2017

TURKISH JOURNAL of CLINICS and LABORATORY

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“…All active lesions showed decreased FDG uptake after treatment [ 47 ]. Ozmen and colleagues [ 48 ] also showed significantly decreased FDG uptake after complete remission of WG in their PET/CT study. FDG-PET/CT is more useful than traditional imaging studies, such as CT, for differentiating between active lesions and residual loci of inflammation in patients with WG.…”

Section: Part II the Usefulness Of Pet/ct Imaging In The Therapy Resmentioning

confidence: 93%

“…In addition, FDG-PET/CT can be combined with other imaging methods to inform selection of biopsy sites. Ozmen and colleagues [ 48 ] also reported PET/CT to be useful for detecting active lesions (except in the kidneys) and for identifying biopsy sites in patients with WG. FDG-PET/CT is more useful than traditional imaging studies, such as CT, for differentiating between active lesions due to WG and residual foci of inflammation.…”

Section: Part I the Usefulness Of Pet/ct Imaging In The Assessment Omentioning

confidence: 99%

Clinical value of whole-body PET/CT in patients with active rheumatic diseases

2014

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Advanced imaging techniques may enable early diagnosis and monitoring of therapy in various rheumatic diseases. To prevent irreversible tissue damage, inflammatory rheumatic disease must be diagnosed and treated in pre-clinical stages, requiring highly sensitive detection techniques. Positron emission tomography (PET) provides highly sensitive, quantitative imaging at a molecular level, revealing the important pathophysiological processes underlying inflammation. This review provides an overview of the current utility of 18 F-fluorodeoxyglucose (FDG)-PET/computed tomography (CT) in patients with active rheumatic diseases such as rheumatoid arthritis, spondyloarthritis, polymyalgia rheumatica, adult-onset Still’s disease, relapsing polychondritis, immunoglobulin G4-related disease, large-vessel vasculitis, Wegener’s granulomatosis, polymyositis, and dermatomyositis. We also discuss the role of FDG-PET/CT in the diagnosis and monitoring of these diseases.

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“…In addition, this technique is beneficial for evaluating recurrence and spatial expansion of WG (11). Ozmen et al evaluated pulmonary and non-pulmonary involvement in a series of 13 WG patients by FDG PET/CT, and found evidence of involvement in the spleen and the adrenal glands in addition to the upper respiratory tract and the lungs (12). They evaluated the response to therapy by FDG PET/CT in only 2 out of 13 cases, and reported either complete resolution or decreased uptake on followup scans.…”

Section: Literature Review and Discussionmentioning

confidence: 99%

18F-FDG PET/CT Findings of a Patient with Wegener’s Granulomatosis Before and After Therapy

Özdemir¹,

Poyraz²,

Şentürk³

et al. 2015

Mirt

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Integration of 2-deoxy-2-[18F] fluoro-d-glucose PET/CT into clinical management of patients with Wegener’s granulomatosis

Abstract: FDG with PET/CT is a valuable tool in the management of patients with WG for a more accurate clinical evaluation regarding disease extension and treatment response.

Cited by 17 publications

References 15 publications

Granülamatosis Polianjitis tanılı beş olgunun Pozitron Emisyon Tomografisi ile değerlendirilmesi

Granülamatosis Polianjitis tanılı beş olgunun Pozitron Emisyon Tomografisi ile değerlendirilmesi

Clinical value of whole-body PET/CT in patients with active rheumatic diseases

18F-FDG PET/CT Findings of a Patient with Wegener’s Granulomatosis Before and After Therapy

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