A variety of naturally occurring (e.g., solar activity) and other (e.g., deliberate attack, residual space object impact) risk factors exist for orbital, aerial and ground-based assets. This paper provides an overview of multiple different risk sources to spacecraft. It then provides an overview of the multi-tier mission/operations architecture. The various types of craft that can participate are discussed as are prospective deployment patterns. Next, a mission plan for a high-resiliency sensing mission is presented. Finally, the paper concludes by considering next steps for testing this designed-forresilience multi-tier architecture.