Integrating genomics education into Nigerian undergraduate medical training - A narrative review

Afolaranmi, Oluwasegun; Salako, Omolola; Okunade, Kehinde Sharafadeen; James, Ayorinde Babatunde; Fagbenro, Gabriel

doi:10.4103/jcls.jcls_6_20

Cited by 4 publications

(8 citation statements)

References 22 publications

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“…In contrast, 51% of medical students in Bosnia and Herzegovinia felt their education was well designed for precision medicine (1). Afolaranmi et al (2021) have highlighted the poor state of genomics education in Nigeria including the lack of su cient quality laboratory exposure of medical students resulting in a consequent relative lack of genomics-based research (27). Our ndings support the need for an improved nation-wide medical school curriculum in Nigeria that is congruent with the current practice needs of modern medicine, and that will serve to update the interests and expertise of future Nigerian physicians to make them competitive in the global medical space.…”

Section: Discussionmentioning

confidence: 99%

Preparedness of Nigerian Medical Students for an Era of Precision Medicine – A Cross-Sectional Survey in Lagos, Nigeria

Ogamba

Roberts

Ajudua

et al. 2023

Preprint

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Background Advances in precision medicine in Nigeria call for a need to improve genomics education and competency among healthcare practitioners to facilitate clinical translation. Due to the paucity of research in this area, this study aimed to assess the preparedness of Nigerian medical students to integrate precision medicine into their clinical practice. Methods This was an institution-based cross-sectional study of 300 4th to 6th-year medical students attending the two fully-accredited colleges of medicine in Lagos, Nigeria between April and October 2022 using an adapted tool administered via Google Forms. The survey assessed awareness, perceived knowledge, ability, and attitudes toward precision medicine as well as ethical concerns and perceptions about their education in precision medicine. Results Awareness of precision medicine terminologies was high (92.0%). Respondents had above-average median knowledge and ability scores and high median attitude scores. Respondents expressed concerns mostly about the misuse of genomic data (35.7%) and the possible widening of socioeconomic disparities (34.0%). Although respondents thought that it is important to learn about precision medicine (65.0%), only 11.3% felt that their education had adequately prepared them. Conclusion These highlight a poor sense of preparedness and the need to improve precision medicine education among Nigerian medical students.

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Section: Discussionmentioning

confidence: 99%

Preparedness of Nigerian Medical Students for an Era of Precision Medicine – A Cross-Sectional Survey in Lagos, Nigeria

Ogamba

Roberts

Ajudua

et al. 2023

Preprint

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“…The attitude scores of participants ranged from 14 to 40, with a median score of 28 (IQR: [24][25][26][27][28][29][30][31][32][33]). The median score on the openness items was 15 (IQR: [12][13][14][15][16].…”

Section: Perceived Attitudes Of Participantsmentioning

confidence: 99%

“…However, to our knowledge, no study has been done in Nigeria to assess medical students' preparedness for an era of precision medicine. With approaches to bridge the gaps in precision medicine in healthcare in Africa, this begs for undergraduate medical students to have a solid foundation to apply genomics medicine to the various specialties by equipping them with the requisite skills and knowledge needed to easily transit into the eld, as has been underscored in other climes [15,[23][24][25][26]. Apart from expertise, different ethical, legal, and social issues (ELSI) arise in precision medicine, such as privacy and con dentiality, racial/ethnic discrimination, in uence on health inequalities, and access and utilization of population genomic data by governments and corporate bodies [1].…”

Section: Introductionmentioning

confidence: 99%

Preparedness of Nigerian Medical Students for an Era of Precision Medicine – A Cross-sectional Survey in Lagos, Nigeria.

Ogamba,

Roberts,

Ajudua

et al. 2023

Preprint

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Background The increasing advances in precision medicine in Nigeria suggest improving genomics education and competency among healthcare practitioners to facilitate clinical translation. Due to the scarcity of research in this area, this study aimed to assess Nigerian medical students' preparedness to integrate precision medicine into their clinical practice. Methods This was an institution-based cross-sectional study of 300 medicine and surgery students in their clinical years attending the two fully accredited colleges of medicine in Lagos, Nigeria, between April and October 2022 using an adapted tool administered via Google Forms. The survey assessed awareness, perceived knowledge, ability and attitudes towards precision medicine, ethical concerns, and perceptions about their education in precision medicine. Multivariate linear regression models were used to assess factors associated with students’ perceived knowledge, ability and attitudes. Results Awareness of genomic medicine terminology was high (92.0%). Respondents had above-average median perceived knowledge, ability and attitude scores. Higher level in medical school was independently associated with lower perceived knowledge (ptrend = 0.003) and ability (ptrend = 0.005) scores, and perceived knowledge score was independently associated with a higher perceived ability score (β: 0.76 95%CI: 0.67, 0.84; p<0.001). Attitude scores significantly increased with increasing medical school year (ptrend = 0.04). The respondents mostly indicated concerns about government and corporate bodies' misuse of genomic data (35.7%) and the widening of socioeconomic disparities (34.0%). Although 65.0% of the respondents thought it important to learn about precision medicine, only 11.3% felt that their education had adequately prepared them for precision medicine, knew who to ask questions regarding genomic testing (10.7%) and felt their professors had encouraged the use of precision medicine (10.3%). Conclusion Our findings highlight gaps in preparedness for precision medicine and a need to improve precision medicine education among Nigerian medical students.

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“…However, the application of personalized medicine might be limited when applied to non-genetic diseases. For instance, the burden of non-communicable diseases is largely considered to be as a result of lifestyle changes and urbanization ( Collins and Varmus, 2015 ; Drake et al, 2018 ; Afolaranmi et al, 2021 ) rather than individualized genetic changes. Nonetheless, the implementation of personalized medicine will result in a paradigm shift from the conventional symptom-based, “trial-and-error” health system to a genome-based approach, thereby, bringing about precision and personalization in disease diagnosis, management, and treatment ( Drake et al, 2018 ).…”

Section: Introductionmentioning

confidence: 99%

Personalizing medicine in Africa: current state, progress and challenges

Owolabi,

Adam,

Adebiyi

2023

Front. Genet.

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Personalized medicine has been identified as a powerful tool for addressing the myriad of health issues facing different health systems globally. Although recent studies have expanded our understanding of how different factors such as genetics and the environment play significant roles in affecting the health of individuals, there are still several other issues affecting their translation into personalizing health interventions globally. Since African populations have demonstrated huge genetic diversity, there is a significant need to apply the concepts of personalized medicine to overcome various African-specific health challenges. Thus, we review the current state, progress, and challenges facing the adoption of personalized medicine in Africa with a view to providing insights to critical stakeholders on the right approach to deploy.

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Integrating genomics education into Nigerian undergraduate medical training - A narrative review

Cited by 4 publications

References 22 publications

Preparedness of Nigerian Medical Students for an Era of Precision Medicine – A Cross-Sectional Survey in Lagos, Nigeria

Preparedness of Nigerian Medical Students for an Era of Precision Medicine – A Cross-Sectional Survey in Lagos, Nigeria

Preparedness of Nigerian Medical Students for an Era of Precision Medicine – A Cross-sectional Survey in Lagos, Nigeria.

Personalizing medicine in Africa: current state, progress and challenges

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