“…Frequent words used by participants are training, communication, change management, compliances, data integrity, regulatory, batch restrictions in different countries, demand sensing or forecasting, temperature sensitiveness, cold chain, third-party providers, restrictions, shelf life, expiry, and auditable planning, and operational barriers in pharmaceutical industries by supply chain extension include difficulties in coordination between multiple stakeholders, quality control problems, difficulties in managing flows and lack of inflexibilities, procurement, and storage problems, and logistics inefficiencies by the low shelf life of medicines [21]. Cost and price barriers by third-party logistics, counterfeiting, drug diversion, and difficulties in monitoring the supply chain are the fundamental nature of the extension and diversity of items [44]. Compared to other industries, managers in the pharmaceutical industry suffer from many constraints, such as counterfeit issues, unfavorable reactions to the patients regarding efficacy, if the temperature is not maintained during product life cycles, manufacturing and labeling issues, transportation and shipment issues, and storing and warehouse issues [3].…”