“…Tumours are classified into immune‐active, immune‐exhausted and immune‐depleted subtypes depending on their immune characteristics. Predominate T‐cell infiltrate and molecular signalling pathways related to the immune classes according to 31 ,105,106,108,110 are shown. CCL, chemokine (C‐C motif) ligand; CTLA‐4, cytotoxic T lymphocytic antigen 4; CXCL, chemokine (C‐X‐C motif) ligand; DC, dendritic cell; iNOS, inducible nitric oxide synthase; LAG‐3, Lymphocyte‐activation gene 3; MDSC, myeloid‐derived suppressor cell; NK, natural killer cell; PD‐1, programmed cell death protein 1; PD‐L1, programmed cell death ligand 1; TAM, tumour‐associated macrophages; TEX, exhausted CD8+ T cells; TGF‐β, transforming growth factor β; TIM‐3, T‐cell immunoglobulin and mucin‐domain containing‐3; TNF‐α, tumour necrosis factor α; Treg, regulatory T cell; TRM, tissue‐resident memory T cell; VEGF, vascular endothelial growth factor.…”