Integrated untargeted and targeted testicular metabolomics to reveal the regulated mechanism of Gushudan on the hypothalamic‐pituitary‐gonadal axis of kidney‐yang‐deficiency‐syndrome rats
Yanwei Lou,
Qinghua Liang,
Ling Xin
et al.
Abstract:Modern studies have shown that neuroendocrine disorders caused by the dysfunction of the hypothalamic‐pituitary‐gonadal (HPG) axis are one of the important pathogenetic mechanisms of kidney‐yang‐deficiency‐syndrome (KYDS). The preventive effect of Gushudan on KYDS has been reported, but its regulatory mechanisms on the HPG axis have not been elucidated. In this study, we developed an integrated untargeted and targeted metabolomics analysis strategy to investigate the regulatory mechanism of Gushudan on the HPG… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.