Integrated proteomic and metabolomic profiling reveals novel insights on the inflammation and immune response in HFpEF
Muyashaer Abudurexiti,
Refukaiti Abuduhalike,
Tuersunjiang Naman
et al.
Abstract:Background
The precise mechanisms leading to the development of heart failure with preserved ejection fraction (HFpEF) remain incompletely defined. In this study, an integrative approach utilizing untargeted proteomics and metabolomics was employed to delineate the altered proteomic and metabolomic profiles in patients with HFpEF compared to healthy controls.
Materials and methods
Data were collected from a prospective cohort consisting of 30 HFpEF… Show more
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