Integrated proteomic and metabolomic profiling of urine of renal anemia patients uncovers the molecular mechanisms of roxadustat

You, Xiaoe; Guo, Baoqiang; Wang, Zhen; Ma, Hualin; Liu, Lixia; Zhou, Ru; Zheng, Yi; Zhang, Xinzhou

doi:10.1039/d3mo00015j

Mol. Omics

2023

DOI: 10.1039/d3mo00015j

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Integrated proteomic and metabolomic profiling of urine of renal anemia patients uncovers the molecular mechanisms of roxadustat

Xiaoe You

Baoqiang Guo

Zhen Wang

et al.

Abstract: Roxadustat (FG-4592) is a hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) indicated for patients with low hemoglobin associated with chronic kidney disease. Due to the various HIF-mediated adaptive responses, FG-4592 has...

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Integrated proteomic and metabolomic profiling of urine of renal anemia patients uncovers the molecular mechanisms of roxadustat

Abstract: Roxadustat (FG-4592) is a hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) indicated for patients with low hemoglobin associated with chronic kidney disease. Due to the various HIF-mediated adaptive responses, FG-4592 has...

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References 38 publications

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