The challenges and opportunities that nations and regions of the world face with regard to food security today and in the future can benefit greatly from scientific and technological innovations that continue to be the hallmark of human ingenuity in this era of increasing global competition for limited resources on planet Earth. Securing food, fibre, feed, and energy for the current inhabitants and future generations is one of the grand challenges facing humans in this century, and perhaps the next one, especially in light of rapid changes in the Earth's planetary system. This handbook is dedicated to the research findings by a team of several hundred distinguished scientists, policy experts, and decision makers from around the world who worked together, through the AgMIP and by way of their national programs and contributions, to assess the current state of scientific understanding and knowledge of the food systems in order to address this global grand challenge.There are several unique features in this handbook and it is the content that sets it apart from other science-based assessments and reports. First, it is solution-oriented in that the findings and recommendations are intended to be actionable by stakeholders and decision makers who were an integral part of the assessment process. This participatory approach enabled the findings and outcomes to be accessible and useful for adaptive measures towards a more sustainable food system for present and future generations. Second, the regional and sectoral focus of the assessment, based on newly developed Representative Agricultural Pathways (RAPs), potential pathways for development that account for specific and unique soil-crop-climate conditions regionally and globally. Third, the multidisciplinary team of scientists and decision makers that AgMIP recruited and engaged in the assessment process facilitated sharing of the best available information and knowledge to accomplish the stated goals of this project.Fourth, these efforts helped in advancing the state of scientific understanding, knowledge, and sharing of and access to attendant capabilities, such as observations, models, and analysis tools, by all those involved in the project without any restriction. This was further enhanced through sharing of the results openly at scientific and technical stakeholder workshops and events, and by including them in vii viii Foreword major international science-based assessments, such as the Global Environmental Outlook-6 (GEO6) and the Intergovernmental Panel on Climate Change (IPCC) assessment reports.The first chapter in this handbook sets the stage by identifying and describing the goals and objectives of this major and seminal scientific effort, and the outcomes of the entire process. It identifies the key ingredients for the success of such efforts (e.g., participatory and stakeholder engagement) and the lessons learned. The subsequent chapters describe in greater depth and detail the soil-crop-climate-specific analyses conducted for specific regions across the g...