Intake of the First-Generation Anti-Histamines in Early Childhood May Have an Adverse Effect on Cognitive Function. Population Based Pharmacoepidemiologic Study in Non-Asthamtic Children
Abstract:As the allergic diseases increase steadily worldwide, the main goal of the study was to assess the association between the early intake of the first-generation sedative antihistamines in young non-asthmatic children and their cognitive function at the age of 7. The size of the exposure effect was measured by the Wechsler intelligence Scale for Children (WISC-R) and adjusted in multivariable models for major confounders known to be important for children cognitive development. The study included 212 children wh… Show more
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