Intake and adherence to energy and nutrient recommendations among women and men with binge-type eating disorders and healthy controls

Wiklund, Camilla; Igudesman, Daria; Kuja‐Halkola, Ralf; Bälter, Katarina; Thornton, Laura M.; Bulik, Cynthia M.

doi:10.1016/j.clnesp.2022.02.111

Cited by 4 publications

(4 citation statements)

References 46 publications

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“…Nutrition data, the intake of food items, beverages, and dishes reported in the food frequency questionnaire Mini Meal Q (MMQ), were linked to the national database of nutrient contents published by the Swedish National Food Agency using an in‐house‐developed python script (Wiklund et al., 2022 ). We estimated differences in energy, macronutrient, and micronutrient intake between OCD and HCs, and within OCD cases before and after ERP using linear regression models adjusting for BMI.…”

Section: Methodsmentioning

confidence: 99%

Longitudinal study of gut microbiome in obsessive–compulsive disorder

et al. 2023

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IntroductionPatients with obsessive–compulsive disorder (OCD) often have limited exposure to a diverse environment and perform repetitive compulsions such as excessive cleaning and washing, which could lead to altered gut microbiome. Therefore, longitudinal studies that investigate changes in gut microbiome before and after cognitive behavioral therapy based on exposure and response prevention (ERP) are warranted.MethodsAll study participants (N = 64) underwent a structured psychiatric diagnostic interview prior to inclusion. Nutritional intake was assessed with a comprehensive food frequency questionnaire. Stool samples were collected from OCD patients before ERP (n = 32) and 1 month after completion of ERP (n = 15), as well as from healthy controls (HCs; n = 32). Taxonomic and functional analyses were performed using data from microbiome whole genome sequencing.ResultsPatients with OCD at baseline reported consuming significantly less fiber than HCs (R2 = .12, F(2, 59) = 5.2, p ≤ .01). There were no significant differences in α‐ and β‐diversity indices, or taxonomic dissimilarities at the species level between patients with OCD and HCs, or within patients before and after ERP. Functional profiling based on gut microbial gene expression was grouped into 56 gut–brain modules with neuroactive potential. None of the gut–brain modules differed significantly in expression between patients with OCD at baseline and HCs or within patients before and after ERP.ConclusionsThe diversity, composition, and functional profile of the gut microbiome in patients with OCD did not differ significantly from HCs and remained stable over time, despite behavioral changes.

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Section: Methodsmentioning

confidence: 99%

Longitudinal study of gut microbiome in obsessive–compulsive disorder

et al. 2023

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“…Moreover, in addition to directly providing heme iron, the consumption of meat and fish in a meal enhances the absorption of nonheme iron [ 18 ]. As a result, those with a vegetarian diet are more likely to have ID compared with those whose diet contains animal products [ 19 ]. Thus, the daily iron intake for individuals with vegan diets should be 1.8-times that of adolescents with omnivorous diets.…”

Section: Adolescents Affected By Idmentioning

confidence: 99%

“…This finding enforces the importance of ongoing nutritional counseling during and after an adolescent receives therapy for their eating disorder. Bulimia nervosa is characterized by repeated episodes of binge eating and compensatory behaviors to prevent secondary weight gain, frequently accompanied by insufficient oral iron intake [ 19 ]. Individuals with ARFID have disruptive eating patterns that result in a failure to meet their physiologic energy needs [ 34 ].…”

Section: Adolescents Affected By Idmentioning

confidence: 99%

Nutritional Strategies for Managing Iron Deficiency in Adolescents: Approaches to a Challenging but Common Problem

Cohen,

Powers

2024

Advances in Nutrition

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“…Another important limitation is the lack of a quantitative measure of dietary intake, which varies between individuals with and without BED or BN (80) and is an important predictor of intestinal microbial composition and diversity (34). Alongside dietary intake, future studies should measure the fecal metabolome and the host and microbial transcriptome, to estimate the joint influence of diet, laxative use, and the composition and functionality of the intestinal microbiota and its metabolites on functional gastrointestinal disorders, which can exacerbate eating disorder symptoms and are common among individuals with eating disorders who report laxative use (81).…”

Section: Original Articlementioning

confidence: 99%

Laxative abuse is associated with a depleted gut microbial community structure among females and males with binge-eating disorder or bulimia nervosa: The Binge Eating Genetics Initiative (BEGIN)

et al. 2023

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Objective: This study assessed the associations of binge eating, compensatory behaviors, and dietary restraint with the composition and diversity of the intestinal microbiota among participants with binge-eating disorder or bulimia nervosa. Methods: We analyzed data from 265 participants aged 18 to 45 years with current binge-eating disorder or bulimia nervosa enrolled in the Binge Eating Genetics Initiative study. We evaluated the associations of binge-eating frequency; presence/absence and frequency of vomiting, laxative use, and compulsive exercise; and dietary restraint with abundances of gut microbial genera, species, and diversity (Shannon diversity, Faith phylogenetic diversity, and Peilou's evenness) from 16S rRNA gene sequencing. General linear regression models adjusted for potential confounders, including age and current body mass index, were used to test associations; p values were corrected for the false discovery rate. Results: The normalized abundance of four genus-and species-level gut microbes and three diversity indices were lower among Binge Eating Genetics Initiative participants who reported any laxative use compared with those who reported no laxative use. Vomiting frequency was positively associated with the normalized abundance of the genus Escherichia-Shigella, a potential pathobiont, although the association was attenuated to nonsignificance after adjustment for age, body mass index, and binge-eating episodes. Conclusions: Laxative use was highly and uniformly predictive of a reduced gut microbial diversity including potential commensals and pathobionts, and should be assessed and accounted for in all future studies of eating disorders and the gut microbiota. Future studies should collect data on specific medications-particularly laxatives-and dietary intake to obtain unbiased estimates of the effect of eating disorders on the gut microbiota and identify potential downstream clinical implications. Trial Registration: ClinicalTrials.gov identifier: NCT04162574.

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Intake and adherence to energy and nutrient recommendations among women and men with binge-type eating disorders and healthy controls

Cited by 4 publications

References 46 publications

Longitudinal study of gut microbiome in obsessive–compulsive disorder

Longitudinal study of gut microbiome in obsessive–compulsive disorder

Nutritional Strategies for Managing Iron Deficiency in Adolescents: Approaches to a Challenging but Common Problem

Laxative abuse is associated with a depleted gut microbial community structure among females and males with binge-eating disorder or bulimia nervosa: The Binge Eating Genetics Initiative (BEGIN)

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