Int&in: A machine learning‐based web server for active split site identification in inteins
Mirko Schmitz,
Jara Ballestin Ballestin,
Junsheng Liang
et al.
Abstract:Inteins are proteins that excise themselves out of host proteins and ligate the flanking polypeptides in an auto‐catalytic process called protein splicing. In nature, inteins are either contiguous or split. In the case of split inteins, the two fragments must first form a complex for the splicing to occur. Contiguous inteins have previously been artificially split in two fragments because split inteins allow for distinct applications than contiguous ones. Even naturally split inteins have been split at unnatur… Show more
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